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Implantation Failure: What Can Prevent It From Happening?

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What is implantation?

Implantation is the attachment of the fertilized egg (embryo) in the endometrium (uterine lining). This usually happens after the embryo has traveled through the fallopian tube on average 9 days (range 6-12 days) after ovulation and fertilization.

What is implantation failure?

In some women, the reason for infertility is so called "implantation failure". Implantation failure refers to the failure of a fertilized egg, the embryo, to implant in the lining of the uterine wall to begin conception and start producing the pregnancy hormone hCG.

The specific cause of implantation failure is often unknown, but here are some possible reasons:

Asherman syndome and other scars in the uterine lining
A significant genetic defect in the embryo
A uterine lining that is not ready for implantation like a too thin endometrium
Chronic endometritis
Embryonic defects
Endometriosis
Progesterone resistance
An immature egg

If you have multiple implantation failures, your doctor can do some tests to try finding out what it could be, though oftentimes no specific reason or treatment is found. One test could be to do an endometrial biopsy to check if you have a chronic infection of the endometrium, the uterien lining (chronic endometritisi).

One known cause of implantation failure is taking high doses of certain hormones, like those which are in birth control pills. Those hormones are part of "Plan B," or the morning-after pill.

What happens to the embryo when there is no implantation?

When there is no implantation, there is usually no embryo developing or the embryo is being absorbed by the body.

What can a woman do to improve chances of implantation?

While there are many myths out there surrounding getting pregnant, when it comes to implantation, there are few things a woman can do to prevent it from happening.

Strenuous exercises are unlikely to prevent implantation.
Straining with bowel movements, for example, will not impact embryo implantation. Constipation is a common side effect of progesterone which slows the digestive tract, but that will not impact implantation.
Jumping up and down or doing physical exercises are also unlikely to prevent implantation.

Read More: Implantation Signs and Symptoms Early Signs You May Be Pregnant Online Pregnancy Test

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How to Help Implantation

Essential Takeaways

There’s not much you can do to interrupt the process of implantation. Exercise, sex, and moderate caffeine consumption are all most likely fine.
Anti-inflammatories are one of the few things you should avoid during the implantation window

If you’re trying to get pregnant, you might wonder if there’s anything you can do to help implantation . In most cases, the answer is no. This might be disappointing, but it’s also reassuring: embryos are resilient little things, and there isn’t much you can do to prevent a viable one from implanting. If you’re looking back over the last cycle wondering why you didn’t get pregnant, it probably had nothing to do with the wine you drank or the hard workout you did.

Below, we look into some of the most common things that women worry might hurt their chances for pregnancy and reveal whether there is any genuine cause for concern.

Can Anti-Inflammatories Prevent Implantation?

Anti-inflammatories are one of the only things that you might want to avoid after ovulation. They are not good for implantation, as they can affect the ability of the uterus to extend protrusions of the uterine lining to dock with the embryo. One study found an 80% increased risk of early miscarriage with anti-inflammatory use around the time of conception.

Anti-inflammatory medication is also not good for young embryos post-implantation. If you need to treat pain after ovulation, consider taking an acetaminophen-based painkiller like Tylenol, instead of an NSAID like Advil.

Can Exercise Prevent Implantation?

In a study published in the journal Obstetrics and Gynecology , women undergoing IVF and who exercised 4 or more hours per week were twice as likely to have implantation failure. Keep in mind that these results may not apply to the general population, and that moderate exercise is good for fertility (and general health!).

It’s most likely fine to continue an exercise routine that you’re already accustomed to, or even to start a new one as long as you ramp up slowly (which is a good idea whether you’re trying to get pregnant or not). The embryo at this stage is half the size of a dust mite. Its activities are occurring at a molecular scale and are not affected by a single intense workout.

There is one exception. If you habitually exercise a lot, don’t give yourself enough rest days, and don’t eat enough for your activity levels, exercise can have a negative impact on your menstrual health . The first sign that something is wrong is often a shortened luteal phase .

If you are doing a lot of intense exercise and you notice that your luteal phase is getting shorter than 10 days, consider backing off—especially during the two-week wait. Your luteal phase should be at least 10 days long to give enough time for implantation to occur.

Verdict: In most cases, exercise cannot prevent implantation.

Can Caffeine Prevent Implantation?

Multiple studies have shown that the risk of miscarriage increases with caffeine intake. Women consuming greater than 200mg (the amount in one cup of coffee) had twice the miscarriage rate (25.5 percent) as compared to non-users (12.5 percent). Another study showed that women who drank more than 200mg of caffeine per day were half as likely to become pregnant per cycle as women who consumed less.

It’s not totally clear why large amounts of caffeine appear to have a negative impact on fertility, but preliminary studies in mice and monkeys suggest that caffeine inhibits egg maturation. An immature egg may not be fertilized and therefore cannot produce a pregnancy.

Verdict: One cup of coffee is fine.

Can Straining While Going to the Bathroom Prevent Implantation?

Progesterone is elevated during the luteal phase, and this can lead to things being a little backed up in the poop department. You wouldn’t be the first woman who wondered, while straining over the toilet, whether it’s possible to dislodge a nascent embryo from the uterine lining.

Good news: This is not going to happen. If constipation could prevent implantation , there wouldn’t be very many successful pregnancies, since it’s so common to be constipated during the two week wait! Before pregnancy, the uterus is completely closed, with all the walls touching each other. That makes for a very safe, secure environment for a newly implanted egg, and it would be almost impossible to physically shake it out of place.

Verdict: Nope.

Can Sex Prevent Implantation?

The two-week wait is stressful, and what better way to relieve stress than sex? When an orgasm sends those dramatic contractions throughout your pelvis, all thoughts of when to test go out the window. But wait a second…can those contractions send anything else out the window?

Don’t worry, you’re not the first person to worry about this. Unfortunately, there haven’t been very many studies looking into it.

One study did find that sex at the time of implantation confers slightly lower chances of conception, though it did not take orgasm rates into account. But another study found that intercourse during an IVF cycle could actually improve pregnancy rates, since exposure to semen is thought to promote embryo development and implantation in animals.

Lots of women get pregnant after copious amounts of sex during the two-week wait, so unless you are having a hard time getting pregnant and want to try something different, or until more studies are done, you probably don’t need to change your current habits.

Some women experience bleeding around the time of implantation , and worry that sex may have somehow caused it, but there is no evidence for this.

Bottom line: unclear, but probably not.

Can Falling or Getting Injured Prevent Implantation?

You fell off your bike/down the stairs/tripped on a banana peel during the two-week wait. Can that somehow shake the egg out of the uterine lining? Unless it was a very traumatic injury, you’re probably fine. Remember, the uterus is an extremely tight and enclosed space at this stage, and it would be very difficult for anything to fall out of it.

Bottom line: probably not.

Can a Hot Tub, Sauna, or Bath Prevent Implantation?

You wanted to get your mind off the two-week wait, and when your friend invited you to a spa day, it seemed like the perfect thing. You happily frolicked between the sauna, the hot tub, and the steam room until suddenly it hit you: can increased body temperature prevent implantation?

There aren’t any studies specifically looking at the impacts of these things on pregnancy rates, but if you want to be on the safe side, you can follow the same advice that pregnant women follow: keep the heat moderate (below 103 degrees Fahrenheit), try not to sit near the inlet that provides newly heated hot water, and take breaks every 10 minutes or so. And a warm bath is definitely okay!

Bottom line: It’s fine to be in a moderately heated environment for a short amount of time.

View sources

Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study.

Caffeinated beverages and decreased fertility.

Intercourse at the Time of Implantation Confers Lower Chance of Conception

The effect of intercourse on pregnancy rates during assisted human reproduction

Exposure to non-steroidal anti-inflammatory drugs during pregnancy and risk of miscarriage: population based cohort study

Effects of lifetime exercise on the outcome of in vitro fertilization.

Lindsay Meisel

Do’s and Don’ts after your Embryo Transfer

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by Dr. Firuza Parikh

The embryo transfer is the final and most crucial step in the IVF implantation process. I would describe it as the most awaited episode in a thrilling season of a TV serial. The transfer itself is relatively quick and painless, but it is the waiting period that can be the most difficult. For two long weeks, patients must wait and hope that the embryos have successfully implanted and begun to grow. It is a time of great anxiety and anticipation. You may be wondering what you should do after your embryo transfer — and what you should avoid doing.

I would like to share some advice about the Do’s and Don’ts after your Embryo Transfer that can increase IVF success. Read this blog to find out more.

Things to remember after Embryo Transfer

After your embryos have been transferred back into your uterus, there are a few things to remember after undergoing embryo transfer.

You can cough and sneeze if you have to. That will not dislodge your embryo. You can get up from the procedure 5 to 15 minutes after ET. After your embryo transfer, you can go home within an hour. You may have some cramping and spotting which is not unusual. Let us know if this happens.

Sneezing and coughing do not affect embryo implantation as the embryo is cushioned inside the uterus and burrows into the bed of the uterus. It does not float freely in the uterus.

Take things easy that day. You can move around but avoid strenuous activity and heavy lifting. Many people move very slowly. You can walk at your average speed.

What not to do after your embryo transfer?

In order to increase the IVF success after embryo transfer, you need to remember a few things. Here are all those things you should not do after embryo transfer.

Don’t go near the cooking place

Be away from the heat of the cooking range, as that can make you uncomfortable. Raising your body temperature can potentially affect the implantation of the embryo and lead to a lower success rate. So, don’t do this after your embryo transfer.

Avoid sexual intercourse

To ensure success after embryo transfer, doctors recommend avoiding sex intercourse for a week to 10 days after the embryo transfer in order to increase the chances of pregnancy success.

Stay away from polluted areas

You can resume your work after a day or two. You do not need to stop working or going to the office. However, there are few restrictions after embryo transfer, for example, do not go to places which are heavily polluted. It might affect your success rate.

Don’t inhale strong-scented substances

Avoid inhaling petrol and diesel fumes by travelling through areas with less traffic or travelling at a time when the traffic is minimal. If you have any concerns, please contact us . You will have to wait for 2 weeks to confirm the pregnancy.

What can you do after your embryo transfer?

You should not forget about the things that decrease the chances of IVF success after embryo transfer. Read below to find more information.

Carry on with your daily chores

Bending, bathing, and taking care of your daily needs are permitted. You can perform light cooking. You can also give yourself a few days off. Just pamper yourself to relax and rest.

Blood Pregnancy Test Results

There are a few things that you can do after you have gotten your blood pregnancy test results. If your hCG levels increase by 60% over 4 days from one test to the next, it’s very likely that the pregnancy is doing well.

If your hCG levels are lower than what is mentioned on the chart, it is recommended that you carry out timely bhCG tests to see the values. This will determine the healthiness of the pregnancy. Ideally, we recommend doing the b hCG till your values reach 20,000 units.

Positive Signs

After that, we will ask you to do your first early pregnancy scan. You can expect to experience a range of pregnancy symptoms, including nausea, vomiting, fatigue, and bloating.

After embryo transfer, it is important to take some precautions and follow a few do’s and don’ts in the first few days. Here are the basics that you need to remember in order to ensure a healthy pregnancy after embryo transfer.

Once again, these symptoms are normal and usually resolve within a few weeks. Be calm. Take support from friends & family.

If you have any questions or concerns, be sure to contact our team of experts at our IVF centre in Mumbai . We would be happy to help guide you through this exciting time!

Also read: 2 in1 IVF: Dual Stimulation IVF Saves your Cost

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Endometrium & Implantation

Embryo Implantation: What Affects Implantation?

July 18, 2022

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Implantation is the next step after fertilization in the reproductive process. Once an ovulated egg meets sperm in the fallopian tube and gets fertilized, the fertilized egg (now called an embryo) travels down the fallopian tube, enters the uterus and attaches itself to the wall of the uterus. Typically, implantation happens somewhere between 6 and 12 days from ovulation.

Even in our peak fertility years, humans have a just ~30% chance of pregnancy each cycle , where the embryo implants safely and its heartbeat becomes detectable. Based on multiple evidence, scientists hypothesize that about 30% of the embryos do not implant at all, and another 30% are lost soon after implantation, usually without ever being detected. (The ratios vary, depending on the study.) But what’s involved in this process? What affects implantation? Let’s look at 3 factors.

How do embryos implant in the uterus?

Implantation is a complex process. Some doctors and scientists call implantation a “black box,” because there’s a lot we still don’t know about this crucial step in a pregnancy. However, we know that at least 3 inter-connected factors are involved: The embryo itself, the uterus and its lining (endometrium), and the hormonal and immunological environment.

Emerging research suggests that an implanting embryo and the cells in the endometrial lining communicate with each other. This chemical communication triggers some important changes in the uterine environment: The structure and functions of the endometrium changes in a process called decidualization to allow the embryo to take up residence in the uterus and start growing.

Implantation is a multi-step process. After ovulation and fertilization, the embryo enters the uterus but keeps floating free for a few days. The embryo then loosely grabs onto the surface of the endometrium . At this stage, the bond is surface-level and unstable, but gradually becomes more stable. Then, the embryo hatches out of its outer layer (called zona pellucida) and “invades” deeper into the uterine tissue.

At this point, implantation is more or less complete, but the placenta – which would supply oxygen and nutrients to the growing baby – isn’t there yet. It’ll take about 8-12 weeks into the pregnancy to fully form. So, the embryo receives all the nutrients it needs from the glands in the endometrium in these early weeks of pregnancy.

What affects an embryo’s chance of implantation?

All 3 factors – the embryo, the endometrium and the environment – have an impact on the success of implantation. Let's take a look at each one.

1. Embryo quality

The health of the embryo itself affects the likelihood of implantation. A surprisingly high percentage of human embryos carry chromosomal abnormalities. Also called aneuploidy, chromosomal abnormalities are the abnormalities in the number and composition of the chromosomes that carry the DNA.

Patly depending on the age of the mother, the rate of chromosomal abnormalities can be anywhere between 10% and over 50% . Some studies suggest that human aneuploidy rate can be much higher. For example, a 2017 study of women under 37 found that a whopping 63% of embryos carried chromosomal abnormalities .

Many chromosomal abnormalities are lethal, and embryos with these abnormalities usually don’t implant or are miscarried very early, often unbeknownst to the women. This is not to be alarmist - it's the nature's way of ensuring healthy pregnancy and healthy babies.

This high rate of aneuploidy is partly why even young, healthy couples at their peak fertility don’t conceive right away. On average, couples in their early to mid-20s take 3-4 months to get pregnant. It typically takes longer for women in their 30s and 40s.

2. The uterus and endometrial receptivity

While much of the scientific attention has been focused on the embryo, some emerging evidence suggests that the readiness of the endometrium may be just as important as embryo quality for successful implantation. We know, for example, that an adequate thickness of the endometrial lining of at least 7-8 mm significantly increases the chance of pregnancy . Even a perfectly normal, healthy embryo may not implant when the endometrium is not thick enough.

The thickness of the endometrium is not the only factor involved. Scientists use the term “endometrial receptivity” to capture all the conditions that facilitate implantation. The endometrium is receptive to implantation for just 3-6 days for most women. In order to embed itself in the uterus and start growing, an embryo has to arrive in the uterus within this implantation window.

Interestingly, embryos can implant even in tissues where they can’t develop further – for example, in the fallopian tube, when it becomes an ectopic pregnancy. Endometrium, on the other hand, has an ability to prevent embryos from implanting when the conditions aren’t right .

Another uterine aspect of implantation is the health of the uterus itself. It needs to be anatomically normal and free of conditions that can interfere with implantation. These conditions can impact implantation through changes in the physical shape of the uterus, its hormonal environment or the level of inflammation.

3. Hormonal and immunological environment

Implantation requires well-timed changes in the hormonal and immunological functions – locally in the uterus, as well as on the systemic level.

Hormonal changes during implantation

Changes in the balance of reproductive hormones facilitate implantation and support the early pregnancy. Progesterone is at the top of the list. Implantation typically coincides with peak progesterone levels , and according to a study of 189 pregnancies, later implantations that didn’t coincide with peak progesterone were less likely to proceed past 6 weeks of pregnancy .

How does progesterone encourage implantation? The rise in progesterone in the days following ovulation thickens the endometrium, ready for implantation. Then, through its action via the progesterone receptors, progesterone regulates many types of proteins that facilitate implantation at precise moments.

There are likely more proteins and molecules involved that we don’t know yet.

This is why women whose progesterone levels remain elevated past their implantation window are 5 times more likely to have a live birth than women whose progesterone levels drop. One of the next-generation ovulation trackers our scientific team recommends, Proov Predict & Confirm Kit, uses a patented method to measure and analyze the level of progesterone byproduct in your urine to assess the quality of your implantation window.

Try Proov kit to understand the quality of your implantation window.

Another key hormone for implantation is hCG, human chorionic gonadotropin. You are probably familiar with hCG as the hormone that pregnancy tests use to detect an early pregnancy. While hCG levels increases as the pregnancy progresses, the very early, small rise in the hCG levels during implantation notifies the mom’s body that there is an ongoing pregnancy, and menstruation should be off the table. hCG also sustains the corpus luteum, so that it continues to secrete the all-important progesterone.

Immunological changes during implantation

At the same time, the mom’s immune system goes through a (pretty remarkable!) transformation to make it possible for the embryo to survive. Only 50% of the embryo’s genetic material is from the mom, with the other 50% coming from the dad. This genetic makeup actually makes the embryo a foreign invader, like a virus, in the eyes of the mom’s immune system.

Normally, the mom’s immune system would attack the invader to defend the body from harm. In a successful implantation, the mom’s immune system transforms itself so that it can tolerate the embryo. The immune system stays accommodating toward the growing baby throughout the pregnancy until delivery.

The downside? Your immunological defenses are lower during pregnancy . This is why women tend to get more infections and the symptoms tend to be worse.

Regulatory T cells in the endometrium , a type of T cell that suppresses immune response to maintain homeostasis and self-tolerance, play an important role in this establishment – and maintenance – of immunotolerance. Another factor is the previous exposures to the partner’s genetic material via his semen . Interestingly, research suggests that progesterone also helps this immunological transformation acting as an anti-inflammatory agent .

What else can impact implantation?

Reproductive processes are like a rocket ship: Everything has to work properly, together and at the precise moments for the project’s success. Implantation is the same. While there are still a lot of unknowns, scientists think systemic health plays an important role in implantation.

Some of these factors, like smoking and alcohol consumption, are within your control. You can also take action with your doctor’s help on others. Here are a handful of factors involved in implantation:

Thyroid health : Thyroid hormones, T3 and T4, regulate the production of progesterone and other reproductive hormones . While the results are mixed, some studies have found that healthy thyroid functions are associated with better chances of implantation .
Vitamin D status : A healthy level of Vitamin D has been associated with better chances of pregnancy . Scientists hypothesize that a part of the mechanism has to do with implantation, partly because endometrium has Vitamin D receptors and partly because of known impact of Vitamin D on placenta formation .
Blood sugar levels : Normal glucose levels are important for pregnancy in general. Based on some animal studies, it’s also possible that healthy blood sugar levels may facilitate implantation by modulating the endometrial functions .
Smoking : While light smoking may not affect the implantation process itself , the more you smoke, the more likely it negatively impacts implantation. There is also strong evidence that smoking in both men and women negatively impacts embryo quality, which is a factor in implantation.
Weight : Obesity appears to have a negative impact on female reproductive health in many ways, including implantation . Some of the observed effects on implantation may be through its impact on egg quality, while others may be through alterations in gene expression, hormone balance and immune response.
Alcohol : Excessive alcohol can increase cellular stress and trigger changes in the hormonal and nutrient signaling pathways. Some studies suggest that these effects of alcohol may reduce the chance of normal implantation .
Endometrial microbiome : A very recent focus of research, the types of bacteria that colonize the endometrium have been suggested as potentially important for successful implantation. Scientists think that what bacterial species dominates your endometrium may have a significant impact on the endometrial cell function and how the local immune system works.

What affects implantation and what you can do

As we've seen, egg and embryo quality, uterine receptivity, and hormonal and immunological environment of the implantation window all impact your embryo's chance of implantation. To support implantation, focus on what you can control - while we can't turn back the clock to make our eggs (or sperm!) younger, there are some lifestyle factors within your control that can contribute positively to implantation.

To understand a key part of implantation, your progesterone levels throughout the implantation and beyond, consider using Proov Predict & Confirm Kit.

Talk to your doctor about what else you can do together to support implantation, and please reach out if we can answer any questions. We are with you.

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Implantation and the Start of Pregnancy

Implantation is when a fertilized egg, or blastocyst, attaches to the lining of the uterine wall. After implantation happens marks the beginning of pregnancy. In fact, the medical experts like the American College of Obstetricians and Gynecologists and the National Institutes of Health agree that a person is not officially pregnant until implantation has occurred.

Implantation occurs eight to 10 days after fertilization. At this point the embryo moves out of the Fallopian tubes and into the uterus, where it burrows into the uterine wall. After implantation, the embryo will continue to grow and develop until it becomes a fetus, 9 weeks after fertilization.

Medically speaking, successful implantation (not fertilization or conception) equals the start of a pregnancy . Learn more about implantation, what happens after implantation, and the early days of gestation.

The Implantation Process

Here's where implantation fits in the journey to pregnancy.

Ovulation : In order to become pregnant, you need to ovulate (release an egg from an ovary into the fallopian tube).
Ejaculation : After sex, sperm travel through the vagina, past the cervix and up into the fallopian tubes . This is where the sperm will most likely join with an available egg.
Fertilization : When the sperm joins the egg and fertilizes it, conception takes place.
Implantation : About 7 days after sex, the fertilized egg attaches itself to the lining of the uterus. This is implantation .

Timing of Implantation

If you have unprotected sex anytime from about five days before to 24 hours after you ovulate, conception can happen. After conception, the process of becoming pregnant still takes several days, because the fertilized egg (now called a blastocyst) has only just begun its long journey.

The blastocyst has to travel from the fallopian tube into the uterus for implantation to take place. As it makes this journey, it grows in size and its cells divide and reproduce.

A type of tissue called trophoblast develops from the fertilized egg and surrounds it. This trophoblast helps to implant the blastocyst once it arrives in the uterus. The trophoblast begins to push its way into the uterine lining. Next, the trophoblast actually pulls the egg inside of the uterine wall. It then directs blood to the fertilized egg.

Implantation takes place about nine days after ovulation. About 25% of women experience bleeding with implantation. At this point, pregnancy has officially begun.

If implantation does not take place, the fertilized egg will leave the body, probably during your period. Conception does not automatically equal implantation or pregnancy.

What Happens After Implantation?

Implantation is the first trigger for the body to start producing hCG (human chorionic gonadotropin, also known as the pregnancy hormone). Pregnancy tests (both home urine tests and blood tests ) look for the presence of hCG to confirm a pregnancy. Implantation must occur for this hormone to be produced.

If you get a positive result on a pregnancy test, then you know that implantation has taken place (since your body had started to produce the hCG hormone, and the test detected this hormone). If you take a pregnancy test before implantation occurs, the test will tell you that you’re not pregnant, even if you have actually conceived. Since hCG is not yet in your system, the test cannot detect it.

Cleveland Clinic. Pregnancy: Ovulation, conception and getting pregnant .

Wilcox, Allen J., et al. “ Time of Implantation of the Conceptus and Loss of Pregnancy .” New England Journal of Medicine , vol. 340, no. 23, June 1999, pp. 1796–99. DOI.org (Crossref) ,. doi: 10.1056/NEJM199906103402304..

How Your Fetus Grows During Pregnancy . American College of Obstetritians and Gynecologists.

Jarvis GE. Early embryo mortality in natural human reproduction: What the data say . F1000Res . 2016;5:2765. doi:10.12688/f1000research.8937.2

National Institute of Child Health and Human Development. What are some common signs of pregnancy ?

Kim SM, Kim JS. A review of mechanisms of implantation . Dev Reprod . 2017;21(4):351-359. doi:10.12717/DR.2017.21.4.351

By Dawn Stacey, PhD, LMHC Dawn Stacey, PhD, LMHC, is a published author, college professor, and mental health consultant with over 15 years of counseling experience.

When Does Implantation Occur? Symptoms, What to Expect

Medical review policy, latest update:.

Updates throughout to expert sources, text, guidelines and formatting.

What is implantation during pregnancy?

When does implantation occur.

What are the signs and symptoms of implantation?

Read this next, light bleeding, abdominal cramps, other possible signs, what is an implantation dip, when should you take a pregnancy test.

Human chorionic gonadotropin (hCG) production begins when the embryo implants in your uterus, and by 19 days after fertilization, hCG levels have built up enough to be detectable in your urine.

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9 Things To Remove To Increase Implantation Success

By: Author Liz Talton

Posted on Published: July 27, 2021 - Last updated: January 19, 2024

Categories Fertility

9 Things To Remove To Increase Implantation Success

Implantation is when an egg embeds in the lining of the uterus.

No one knows the exact moment implantation occurs because it’s different for each woman depending on the time of ovulation.

However, science agrees an egg implants between days 6 to 12 after ovulation.

Since this is a fragile timeframe, you need to take special care not to do anything that might affect the success of implantation.

It’s estimated that 40% of eggs never implant resulting in a failed cycle.

To increase your chances of successful implantation, you need to eliminate certain things that could interfere with it.

Let’s take a look at 9 things that can negatively affect implantation success.

Disclosure: Bear in mind that some of the links in this post are affiliate links and if you click on them to make a purchase I will earn a commission. Keep in mind that I link these companies and their products because of their quality and not because of the commission I receive from your purchases. The decision is yours, and whether or not you decide to buy something is completely up to you.

Everyday Things To Remove To Increase Implantation Success

1. taking anti-inflammatories.

Anti-inflammatories are a class of medications that reduce swelling and inflammation in the body.

Some common over-the-counter medications (also known as NSAIDs) are Advil, Aleve and Motrin. But what’s the big deal in taking anti-inflammatories around the time of implantation?

A study found taking anti-inflammatories after ovulation increased miscarriage rate by 80%.

Miscarriage rates increase with the use of anti-inflammatories because they prevent the uterine lining from developing a thicker wall.

Without a thick wall to grab and implant in, an egg doesn’t attach.

It’s best to avoid anti-inflammatories all together after ovulation!

Anti-inflammatory medication can be replaced with an acetaminophen medication like Tylenol.

Tylenol is considered safe to take before and during pregnancy.

3. Too Much Caffeine

Who doesn’t love a cup of coffee (or 12 cups) a day? But caffeine is a double-edged sword.

While some studies point to the great health benefits coffee provides, too much caffeine can hinder implantation.

So how much caffeine can you have after ovulation?

200 mg’s or two cups of coffee .

Multiple studies point to an increased risk of miscarriage in women who consumed over 200 mg’s.

In fact, those who drank over 200 mg’s of caffeine doubled their risk of miscarriage.

In a 2011 study, the British Journal of Pharmacology discovered that caffeine relaxes the muscles of the fallopian tubes.

When the fallopian tube muscles relax, an egg is not able to reach the uterus for implantation.

The best way to lower your miscarriage rate during the luteal phase is by watching your caffeine intake to make sure it stays below 200 mg’s.

This is also the recommended daily limit for pregnancy as well.

Here’s a quick list of foods with high amounts of caffeine :

Energy drinks
Tea (For example: Green tea)
“Power” or nutrition bars (always read the labels)
Coffee-flavored yogurt and frozen treats

If you’re unsure of whether something has “hidden” caffeine read the label just to be sure!

4. Eating Too Much Gluten

You’ve probably heard in the news recently that many people are going “gluten-free.”

Many people are discovering they have an autoimmune disorder which makes them sensitive to the protein in wheat, barley and rye (gluten).

But what does a sensitivity to gluten have to do with fertility and implantation?

The Journal of Obstetrics and Gynaecology Research discovered that infertile couples have a high rate of celiac disease than those with no fertility issues.

That’s because celiac disease in women can lead to secondary amenorrhea and fewer ovulations.

In men, celiac disease lowers testosterone levels needed to make normal sperm.

While this is significant research… It should be noted the link between infertile couples and celiac disease is one of many issues affecting fertility.

I’m not saying you need to be “gluten-free” to aid implantation.

However, if you’re exhibiting symptoms of celiac disease it’s important to talk with your doctor about the possibility of having the autoimmune disorder.

Especially if you are having trouble conceiving.

Women who have celiac disease have increased menstrual issues and fewer ovulations.

Without regular ovulation, implantation of an egg in the uterus cannot take place.

Remember: You should not go “gluten-free” unless directed by a doctor!

5. Not Controlling Stress Levels

It’s impossible to get rid of the stress that trying to conceive causes. But you can try to lessen it!

I’ve said it many times before throughout other articles… Not all the stress in your life can be controlled.

You simply cannot control what other people say or do that may cause you stress.

Even though it’s not always possible to control stress, stress adds up to be detrimental to your fertility health.

That’s because stress does not only affect you mentally, but also physically.

When you’re experiencing extreme amounts of stress it affects your body’s ability to produce FSH and LH are greatly reduced . Both FSH and LH are crucial for the development of mature eggs.

If you’re under stress and LH is decreased it could delay or cause your luteal phase to last longer than normal.

That means your menstrual cycle will become disrupted and implantation may not occur.

So how do you manage stress levels to increase your chances of a successful implantation?

Try the following ways to relieve stress:

Find a support network
Journal your thoughts
Practice deep breathing
Say “No” to certain situations and people causing you stress

6. Not Taking A Multivitamin

Most people cannot get all their needed daily vitamins and minerals from diet alone.

Thankfully, a multivitamin will take care of your nutritional gaps.

Your body depends on certain vitamins and minerals to function properly.

Without certain vitamin needs being met, even the menstrual cycle will begin to suffer.

Once anything reproductively decreases, implantation also begins to suffer, lowering your chances to increase implantation success.

Although a regular women’s multivitamin will give you your daily dose, there are specialty multivitamins designed for women who are trying to conceive.

Fertility Enhancing Multivitamins:

ConceivePlus Fertility Prenatal Multivitamin
UpSpring Baby Natural Prenatal Multivitamin
Pink Stork Total Prenatal Vitamin
FertilHerb Herbal & Multivitamin For Women

7. Using A Hot Tub

Yes, a spa day with hot tubs and saunas are great for stress relief and are normally recommended.

But, beware of hot tubs and saunas!

Women who are trying to conceive need to stray on the side of caution when it comes to heated environments.

It is best to abide by the same rules that pregnant women do… Keep the temperature at 103 F or below!

While there’s no specific studies that point toward heated environments and implantation, but it’s better to be safe!

Anything that could disrupt your chances to increase implantation success is a no go.

9. Not Eating A Fertility Based Diet To Increase Implantation Success

There’s a diet for everything now-a-days and that includes fertility. Getting pregnant is big business and you need to be in top physical condition.

To increase your chances of a successful implantation, start eating a fertility based diet !

The Fertility Diet is fairly straight forward and easy to follow.

Here are some key points from the diet to give you a crash course:

Avoid processed forms of soy
Avoid sugary drinks (drink coffee and tea in moderation)
Eat whole foods over processed ones
Avoid artificial sweeteners and eat natural sugars instead
One to two servings of full-fat dairy per day
Eat more plant protein, less red meat and more fish
Substitute processed carbs for complex carbs
Increase plant-based fats

Obviously, this is an extremely quick crash course! To better understand the diet just purchase The Fertility Diet book.

That’s literally all you need to increase your overall fertility and increase implantation success.

While The Fertility Diet book will provide you with an easy science backed diet plan, it only comes with a week’s worth of food ideas.

Honestly, to take the guess-work out of meal planning, purchase a cookbook based around the fertility diet.

I highly recommend the book Fertility Foods: 100+ Recipes To Nourish Your Body While Trying To Conceive.

If you or someone you know is struggling with faith during infertility or trying to conceive, this book is a perfect companion!

When you can’t find the words to pray provides you with…, a topic related to infertility each day, 3 bible verses focused around the topic of the day, a prayer per day, click now to purchase on amazon kindle.

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5 Things You Must Avoid During Implantation

Embryo implantation happens when an embryo binds to the wall of the womb in the endometrial lining. In IVF, it takes a period span of about six to ten days after the egg recovery process, this is on top of the one to five days after the embryo transfer. This process is equal to about days 20 to 24 of the normal 28-day menstrual period.

There are things a person can do in this case any woman trying to get pregnant via implantation. Especially during the two-week wait for implantation to take place. Often a little a person can do to prevent the failure of implantation. Embryos are strong tiny things, a good one would not be prevented by anything from implantation. If implantation failed in the previous attempt there is no need to worry, this is due to the fact that it has nothing to do with anything they drunk like wine or engaging in routine exercises. We will look into some of the most common things that women worry about when it comes to implantation and determine if they really present is any genuine cause for worry.

Things To Avoid During Implantation

A woman should avoid the use of anti-inflammatories.

After ovulation, a woman should avoid completely the use of Anti-inflammatories. They are deemed not good for implantation of the ovum, they affect the ability of the womb by reducing its possibility of developing protrusions of the uterine wall to link with the embryo when it is forming. Studies have shown an increased risk of up to eighty percent of failure of implantation with the use of anti-inflammatory especially during the time of implantation.

Excessive Intake of Caffeine During Implantation

There is a need for a woman to avoid extremes of temperature, avoiding engaging in vigorous exercise and sexual intercourse, avoid foods that are considered to be high glycemic foods or even skipping meal times.

It is highly recommended to stick to food that is considered to be regular and made up of the whole, not excessively processed, sugary, sweets, simple carbohydrates and refined grains ( these are classified as high glycemic foods) this helps in maintaining the normal levels of glucose in the body .

The levels of glucose in the body, whether high or low can have a negative impact on the flow of hormones in the body, regulation of inflammation of the body, and the success of the embryo implantation and its overall development in the body.

[ Read – Precautions During Early Pregnancy To Avoid Miscarriage ]

Things to Implantation Successful

Things to make implantations successful include the quality of the embryo on top of the uterus’s receptivity. The normal characteristics of the chromosomes are another factor that plays part in the successful implantation. The characteristics become reduced as a woman ages which plays a huge part in the failure of embryo implantations with age. A woman has to be in the perfect health character to have high-quality eggs which produce healthy embryos for a successful implantation too.

Foods for implantation of IUI, these foods include Prenatal vitamin which improves the development of the follicle, while improving the quality of the egg, boosts the nutrients found in the walls of the uterus. Pineapple which boosts implantation for it contains a high amount of an anti-oxidizing enzyme known as Bromelain.

A woman trying to conceive should ensure that they consume plenty of anti-inflammatory foods. These prevent inflammation which tends to lead the body attacking and rejecting the sperm, increase the effects of hormonal imbalances while causing the uterus not suitable for the development of the uterus. These anti-inflammatory foods include fresh and vegetables which have not been excessively processed, fruits, nuts, and seeds. Bone soup or broth is good for the development of the eggs before evolution, on top of for the development of the implanted embryo after implantation.

Eating of blood nourishing foods is very important for embryo implantation. Such foods include dark meat chicken, grass-fed beef, bison and/or lamb, dark leafy greens that are cooked (kale, cabbage, chard, collards, broccoli, bokochoy), any dark berries (blackberries, raspberries, mulberries, goji berries, and grapes). Seaweeds and algaes (micro-algae, for example, spirulina or chorella). Gelatin and/or collagen such as Great Lakes Grassfed Gelatin. Blackberry or raspberry leaf tea. Beets. Dates. Nutritional Yeast.

[ Read – Important Medical Tests During Pregnancy ]

Things Which Prevent Implantation of Embryo Depend Mainly on Two Factors which Include

The quality of the embryo
And the receptiveness of the uterus to the embryo

The implantation can also be prevented by cases of chromosomal abnormalities found in the embryo. These abnormalities tend to increase with age in women which in turn reduces the chances of implantation. The egg may at times be unhealthy or has poor quality, this results in embryos which are poor in health and are do not have the ability to implant as required.

Some activities a woman may engage themselves during implantation are very unlikely to affect it or not the embryo implants. The added stress which is unnecessary at this time, in turn, may affect the implantation process. There is a need for relaxation for implantation to take place successfully.

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718-GENESIS

Can I fly after my fertility treatment?

Flying after fertility treatment is a very common question brought up by many patients. Often times, a mixed or incomplete perspective is given both from the provider and from online sources. This blog post will aim to clarify this.

The first question to ask is what is the main concern regarding flying after an insemination or IVF/ embryo transfer cycle? In a nutshell, the concern is radiation exposure.

Is radiation exposure dangerous?

Now at first, the thought of radiation exposure leads to foreboding thoughts in many people. Let’s make it clear that radiation is all around us and we are exposed to it 24/7, 365 days per year. Our bodies have powerful tools that protect us from this background radiation. One of the factors that influences the amount of radiation we receive is where we live; the higher up we live, the less atmosphere there is to protect us from radiation from space. While you’re on a plane, there is a whole lot less atmosphere blocking this radiation.

Take the Next Step - Schedule an Appointment

Onto the next question, how much more radiation do we get when we fly? Well before we answer that question, we first need to understand that radiation really gets dangerous when we go past a certain total dose over a year. Compared to the dose we get in one year from background radiation, a coast-to-coast flight is about 1/10 of the background radiation in that time.

Can radiation exposure affect my embryo?

Now that we know what the level of radiation exposure is, can it do anything to an embryo? In a nutshell, it shouldn’t. While there are no studies looking at flight effects on women immediately after fertility treatment, the body-of-knowledge we have is reassuring. As mentioned, a coast-to-coast flight adds only 10% to our yearly average radiation exposure. There are women who live in areas with much higher yearly background radiation (like Denver, Colorado) and there is no evidence of adverse effects in these women. Therefore, this 10% increase in one flight should not logically have a negative effect. Radiation intensity decreases as it passes through tissue; therefore the vast majority of radiation is absorbed by a woman’s body before it could ever reach an embryo.

In short, patients can fly after insemination or IVF. Implantation ultimately depends upon a healthy embryo finding the right spot in a healthy uterine lining. The success of the subsequent pregnancy depends upon factors that far outweigh any added radiation exposure from a flight.

If you would like to learn more about GENESIS Fertility New York or are ready to schedule an appointment , please speak with one of our representatives at 718-GENESIS .

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Is it safe to travel to high altitudes while pregnant?

Take care while traveling to high altitudes while pregnant: It isn't always recommended, depending on where you go and how you respond to being there.

At high altitudes, less oxygen is available, which means you'll tire more easily. It also means your baby will get less oxygen, which can negatively affect growth and development.

There isn't much research on the effects of traveling to high altitudes during pregnancy. One study of about 450 women who frequently traveled to and exercised at high altitudes during pregnancy didn't find increased risk of complications, though the study's authors said further research is needed to be sure it's safe.

The Centers for Disease Control and Prevention recommends that pregnant women who are traveling avoid staying at altitudes at or higher than 8,500 feet above sea level for more than a few days, and if possible, avoid sleeping at altitudes higher than 12,000 feet. (Denver is 5,280 feet above sea level and would probably be fine, for example; but Pikes Peak, at more than 14,000 feet above sea level, might not be safe.)

Women respond differently to high altitudes during pregnancy. The symptoms of altitude sickness are often similar to typical pregnancy symptoms – dizziness , shortness of breath , lightheadedness, headaches , and trouble sleeping – so it can be hard to tell if you're suffering from altitude sickness or just going through pregnancy. But if you're getting less oxygen than you're used to and you can feel it, your baby may not be getting as much oxygen, either.

If you feel sick while traveling at higher altitudes than you're used to, go to a lower altitude. And if you still don't feel well after you descend, seek medical care.

The CDC also recommends avoiding strenuous physical activity while at high altitudes during pregnancy (unless you're already trained for exercise at high altitude), since you may experience breathlessness and palpitations. If you're planning a vacation at a higher elevation, plan extra time to acclimate before you jump into any physical activity, and you may need to avoid some activities altogether , like skiing or hiking.

One of the biggest concerns about traveling to higher altitudes during pregnancy is these locations are often remote and far from medical care. Some pregnant women need to be especially careful in these situations. If you have hypertension , preeclampsia , or any other high-risk pregnancy condition, going to high altitudes may make your condition worse – and you could be far from the care you need in case of an emergency. Talk with your healthcare provider before making travel plans.

Research shows that repeated exposure to hypoxia – not getting enough oxygen – during pregnancy increases your risk of preeclampsia and can impact your baby's growth. But if you're just traveling to a high altitude for a few days during your pregnancy and you don't experience noticeable altitude sickness, there's no need to worry.

As for women who live at altitudes higher than 8,500 feet, their bodies have made adjustments over time, including higher levels of red blood cells (more hemoglobin), increased numbers of small blood vessels, and increased proteins in the muscles that store oxygen. These adaptations help people function at higher altitudes.

Babies born to moms living at high elevations tend to be smaller than babies born at lower altitudes. Pregnant women living at high altitudes are at two to three times greater risk of preeclampsia and intrauterine growth restriction . For women whose ancestors lived at high elevations for thousands of years (such as those in Bolivia, Peru, or Tibet), the risk of growth restriction is reduced due to evolutionary adjustments, although their babies are smaller on average than those at lower altitudes.

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Is it safe to fly while I'm pregnant?

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Is it safe to travel at high altitudes with a baby?

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Winter activities to avoid during pregnancy

Altitude sickness

BabyCenter's editorial team is committed to providing the most helpful and trustworthy pregnancy and parenting information in the world. When creating and updating content, we rely on credible sources: respected health organizations, professional groups of doctors and other experts, and published studies in peer-reviewed journals. We believe you should always know the source of the information you're seeing. Learn more about our editorial and medical review policies .

CDC. 2019. Pregnant Travelers. http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-8-advising-travelers-with-specific-needs/pregnant-travelers Opens a new window [Accessed November 2021]

Jean D, et al. 2012. Travel to high altitude during pregnancy: Frequently asked questions and recommendations for clinicians. High Altitude Medicine and Biology 13(2):73-81. http://www.ncbi.nlm.nih.gov/pubmed/22724609 Opens a new window [Accessed November 2021]

Julian CG, et al. 2014. Inhibition of peroxisome proliferator-activated receptor gamma: A potential link between chronic maternal hypoxia and impaired fetal growth. FASEB Journal 28(3):1268-79. http://www.ncbi.nlm.nih.gov/pubmed/24307415 Opens a new window [Accessed November 2021]

Julian, CG. 2011. High altitude during pregnancy. Clinics in Chest Medicine 32(1):21-31. http://www.ncbi.nlm.nih.gov/pubmed/21277446 Opens a new window [Accessed November 2021]

Zamudio, S. 2007. High-altitude hypoxia and preeclampsia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428070/ Opens a new window [Accessed November 2021]

Keyes L, et al. 2016. Outdoor Activity and High Altitude Exposure During Pregnancy: A Survey of 459 Pregnancies. Wilderness & Environmental Medicine 27(2):227-35. https://www.wemjournal.org/article/S1080-6032(16)00107-1/fulltext [Accessed November 2021]

Krampl, E. 2002. Pregnancy at high altitude. Ultrasound in Obstetrics & Gynecology 19:535-39. https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1046/j.1469-0705.2002.00738.x Opens a new window [Accessed November 2021]

Palmer SK, et al. 1999. Altered blood pressure course during normal pregnancy and increased preeclampsia at high altitude (3,100 meters) in Colorado. American Journal of Obstetrics and Gynecology 180(5):1161-68. https://pubmed.ncbi.nlm.nih.gov/10329872/ Opens a new window [Accessed November 2021]

Keyes L, et al. 2003. Intrauterine growth restriction, preeclampsia, and intrauterine mortality at high altitude in Bolivia. Pediatric Research 54:20-25. https://pubmed.ncbi.nlm.nih.gov/12700368/ Opens a new window [Accessed November 2021]

Glyde Julian C, et al. 2009. Augmented uterine artery blood flow and oxygen delivery protect Andeans from altitude-associated reductions in fetal growth. American Journal of Physiology 296(5):1564-75. https://pubmed.ncbi.nlm.nih.gov/19244584/ Opens a new window [Accessed November 2021]

Rebekah Wahlberg is a senior associate editor and baby name trends specialist at BabyCenter, the world's number one digital parenting resource. She lives in Southern California with her silly dog Booger, where she enjoys hiking, yoga, and watching Netflix when she "should" be reading. Wahlberg is passionate about creating content that helps parents and parents-to-be equip themselves with everything they need to succeed.

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Home » Does Travelling After Embryo Transfer Affects The Pregnancy Outcome?

Does Travelling After Embryo Transfer Affects The Pregnancy Outcome?

Introduction.

The process of in-vitro fertilization (IVF) involves many important steps. Improvements in ovulation induction, oocyte retrieval and laboratory techniques to achieve maximal rates of fertilization and embryo development have resulted in at least one embryo transfer in 90 % of all cases where oocytes have been retrieved (1). Embryo transfer (ET) is the final and most crucial step of IVF. The successful pregnancy outcome is predicted by the implantation of embryo in uterus.

The process of implantation involves two main components, a healthy embryo that should have the potential to implant and a receptive endometrium that should enable implantation. The “cross-talk” between the embryo and the endometrium that finally leads to apposition, attachment and invasion of embryos is mandatory for successful implantation and subsequent normal placentation. [2.3]. Any abnormality attributed to the embryo, the endometrium or the immune system will result in implantation failure. Therefore, travelling per se will not affect any of the above factors responsible for implantation of embryo.

Earlier there were many studies to evaluate the effect of bed rest on pregnancy rates after embryo transfer. This is the first study to compare the pregnancy rates in patients who travelled to their countries with the patients who stayed back in Delhi after embryo transfer.

Materials and Methods

A retrospective analysis was done in 100 infertile females with age till 40 years who underwent IVF from January 2016 to June 2016. They were divided in 2 groups – the females who went back to their own country after 3 days of embryo transfer (48 females – Group 1) and who stayed back in Delhi (52 females – Group 2). The mean patient age, number of embryos transferred (1,2,3,4), grade (a or b), easy or difficult transfer and endometrial thickness are comparable in both the groups.

Ovarian stimulation was started on day 2 with gonadotropins, recombinant human FSH(rhFSH, Folisuge; Intas Pharmaceuticals Ltd, India or Gonal F; Merck Serono S.p.A, Italy) or highly purified menotropin HMG (hpHMG, Menopur; Ferring GmbH, Germany) in the dose of 225 to 450 IU, depending on patient prole (age, BMI, previous dose of gonadotropins) till day 6 of period followed by transvaginal follicular monitoring and dose was adjusted according to ovarian response. When follicles reached 13 to 14 mm, daily subcutaneous injection of GnRH antagonist, 0.25 mg Cetrorelix (Cetrotide, Merck Serono S.p.A, Italy), was given to trigger ovulation. Transvaginal oocyte aspiration was performed before 36 h, under ultrasound guidance, using Wallace OPU needle and Cooks gamete buffer media. Embryos were further cultured in Cooks fertilization/cleavage/ blastocyst media.

Embryo transfer was done on Day 2 in all the subjects under transabdominal USG guidance (with full bladder). After gentle insertion of speculum and suction of cervical mucus, soft outer sheath was inserted till the level of internal os. It was followed by insertion of the soft Cooks Guardia Access echotip ET catheter containing embryos in 10 mcl media and 5 mcl air bubble on both sides of the media and then 3 or 4 embryos were placed in mid uterine cavity.

Luteal support was added in the form of vaginal and injectable progesterone. Beta hcg was done after 14 days of the embryo transfer. (We had not taken the institutional review board (IRB) approval of this study as it was a retrospective study and we collected the data when their pregnancy test was already positive either they stayed or went back to their place).

The demographic prole for the patients was summarized in Table 1. The embryo transfer parameters were shown in the Table 2. All the parameters related to embryo transfer showed no significant difference in both the groups. The groups were also compared that whether they stayed in Delhi or they went back to their country by Fight affected the pregnancy rates or not (Table 3).

In IVF treatments, rest for a varying period of time is commonly recommended after embryo transfer (ET). However, the scientific basis for this practice remains to be determined. In this context we performed this research to investigate whether this advice is sound or not. In our study, the pregnancy rates were higher in females who went back to their own country.

The implantation failure is the reason of IVF failure and mechanical expulsion of the transferred embryo is a possible cause of failure of implantation. This may be the reason why most women are asked to stay in bed for several hours following ET. However, this has never been shown to be related to a higher success rate. Furthermore, an immediate return to routine daily activities, may lead to a decrease in maternal stress and anxiety following ET (4). There are studies that evaluated the effect of bed rest and mobilization following embryo transfer on the results of in vitro fertilization. Gaikwad S et al studied the influence of 10 minutes of bed rest after ET on the achievement of a live-born infant (LBI) in 240 recipients of IVF with donor eggs which showed that the bed rest immediately after ET has no positive effect and in fact can be negative for the outcome may be due to increase in stress levels (5). Küçük, M also recommended that the patients should not be encouraged to rest in bed after ET and should maintain their routine physical activities during IVF (6). Li B et al performed a systematic review and concluded that there was insufficient evidence to support the routine use of bed rest to improve pregnancy outcome in women undergoing ET in IVF cycles(7).

A systematic review of the literature was conducted which examined each of the major steps of embryo transfer. In this review,14 studies were included to assess that the bed rest or ambulation affect IVF pregnancy and live-birth rates and none of them demonstrated a benefit of bed rest after ET of any duration (8).

As we know many studies were done to evaluate the effect of bed rest on pregnancy rates after embryo transfer. This is the first study to compare the pregnancy rates in patients who travelled to their countries with the patients who stayed back after embryo transfer.

India is a growing destination for medical tourism and people from all over the globe are coming for IVF treatment to our country. We believe that encouraging patients to follow their daily routine immediately after ET or travelling back to their own place may help them to cope with anxiety and they may be more stress free due to more economical, most comfortable life with same cultural habits at their own place.

Gonen Y, Dirnfeld M, Goldman S, Koifman M, Abramovici H. Does the choice of catheter for embryo transfer inuence the success rate of in-vitro fertilization? Hum Reprod. 1991 Sep;6(8):1092-4.
Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Updat. 2006;12:731–46.
Fukui A, Funamizu A, Yokota M, Yamada K, Nakamua R, Fukuhara R, et al. Uterine and circulating natural killer cells and their roles in women with recurrent pregnancy loss, implantation failure and pre- eclampsia. J Reprod Immunol. 2011;90:105–10.
Craciunas L, Tsampras N. Bed rest following embryo transfer might negatively affect the outcome of IVF/ICSI: a systematic review and meta-analysis. Human Fertility 2016; 19: 16-22.
Gaikwad S, Garrido N, Cobo A, Pellicer A, Remohi J. Bed rest after embryo transfer negatively affects in vitro fertilization: a randomized controlled clinical trial. Fertil Steril 2013;100:729–35, Level I.
Küçük, M. Bed rest after embryo transfer: is it harmful?. Eur J Obstet Gynecol Reprod Biol. 2013; 167: 123–126.
Li B, Zhou H, Li W. Bed rest after embryo transfer. European Journal of Obstetrics and Gynecology and Reproductive Biology 2011; 155(2): 125-128.
Practice Committee of the American Society for Reproductive Medicine. Performing the embryo transfer: a guideline. Fertil Steril. 2017;107:882–896.

Original Research Paper Published on GLOBAL JOURNAL FOR RESEARCH ANALYSIS

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C1 Sector 26 Opposite Pillar No. 18 of Noida Bypass Flyover, Noida, Uttar Pradesh 201301
Office No. :-1018, 10th Floor, Galleria Tower, DLF-4, Gurgaon (Haryana) 122009
[email protected]

Disclaimer – Dr Kaberi is not associated with any Hosptial/Clinic other than “Advanced Fertility and Gyne Center (AFGC)”. AFGC has only four centers at present 1. “ Lajpat Nagar ” 2. “ CR Park Delhi ” 3. “ Noida ” 4. “ Gurgaon “.

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What Happens After Implantation? The Process of Conception Explained

Jun 30, 2023
8 mins read

Everything you need to know about conception. What is necessary for sperm and egg to meet at the right moment? What are the conditions for successful implantation? And what can disrupt these processes?

The beginning of new life is one of the most fascinating biological processes there is. The successful fertilisation of a mature female egg and its implantation in the uterine lining (also known as the endometrium ) play a decisive role.

In this article, we look at how the sperm and egg come together and the complex processes that take place in a woman's body when pregnancy begins. What must occur for the mature egg to meet the sperm at the right moment and be fertilised? What conditions are needed for successful implantation? And what can prevent these processes? Below, we have summarised everything you need to know.

What happens during fertilisation of the egg?

Fertilisation of the mature egg cell ( ovum ) by the male sperm cell normally occurs in one of the fallopian tubes . After ejaculation, the sperm swim through the cervix into the fallopian tube. When a sperm reaches the egg, it can dock to the cell membrane of the egg and penetrate the outermost layer of the cell. While more than one sperm can dock on the outer membrane of the egg, only one can penetrate and fertilise the egg.

If a sperm has successfully penetrated, the two cells can fuse with each other. Both cells detach from their shells and then form a new cell, with 23 chromosomes from the mother and 23 from the father. The new cell (called a zygote ) consists of 46 chromosomes in total. This means that the fertilised egg cell now contains the genetic information of the mother and father. Depending on whether the fertilising sperm carries an X or a Y chromosome, the newly-formed zygote will be either female or male.

When can fertilisation occur?

To understand when fertilisation can occur, we look at the female menstrual cycle . The cycle begins on the first day of menstruation and ends the day before the next menstruation. An average cycle lasts 28 days, but cycle length can vary from woman to woman, or month to month. Cycles between 21 and 35 days are considered normal. If your cycle is not within this range, it may be a good idea to consult with your doctor or a fertility specialist.

The female ovarian cycle includes four phases:

Menstrual phase : the uterine lining (endometrium) is secreted with menstruation.
Follicular phase : follicle-stimulating hormone (FSH) is produced and promotes the maturation of the egg. A surge in luteinising hormone (LH) triggers the start of ovulation , which is the release of a mature egg.
Ovulatory phase : a 12-24 hour time period where the mature egg travels from the ovaries to one of the fallopian tubes.
Luteal phase : hormones that prepare the body for pregnancy are produced and the uterine lining is prepared for the fertilised egg to implant.

During ovulation, the mature egg enters the fallopian tube where it can meet the male sperm. Even if you do not have sexual intercourse during the 12-24 hour ovulatory phase , there is possibility that the egg can be fertilised. This is because although an egg survives in the fallopian tube for only 24 hours, sperm can survive for up to five days in the female reproductive tract. Therefore, there is a fertile window of six days ( five days before ovulation and the day of ovulation itself).

Several methods are available to help you determine your fertile window: apps that track the menstrual cycle, taking your temperature, examining the cervical mucus, and using ovulation tests.

What happens during implantation of the fertilised egg?

At the time of implantation , the fertilised egg embeds itself in the wall of the uterus and attaches to the endometrial tissue. This process is complex and is influenced by a variety of factors. Implantation in the uterus can only occur during a limited period time called the implantation window. Research has shown that the implementation window may vary, but it is typically said to occur 6–10 days after ovulation, lasting between 3–6 days .

The process of implantation unfolds as follows:

The fertilised egg travels to the uterus. The fertilised egg makes its way through the fallopian tubes into the uterus. Around one week after fertilisation, the egg will reach the fallopian tubes.

From the time of fertilisation, cell division begins. The identical cells produced are called blastomeres. Once there are 16 blastomeres, they form a sphere of cells called a morula. The term 'morula' means mulberry in Latin, which is what the cell cluster looks like at this stage. Later, it transitions into the blastocyst and the blastocyst stage begins. This consists of an outer layer of cells, which later becomes the placenta, and an inner layer of cells, from which the embryo develops.

The fertilised egg attaches to the endometrium. When the blastocyst finally reaches the uterus, it attaches to the uterine wall and enters into a dialogue with the endometrium. At this time, various hormones and enzymes are released that enable the blastocyst to penetrate the mucosa (a soft mucous membrane that lines the uterus).

The fertilised egg embeds in the endometrium. The blastocyst finds its place for implantation and embeds itself in the endometrium. It covers itself completely with the uterine lining and connects to the female bloodstream. Thus, it has successfully nested and the body receives the information that it is now pregnant.

Following implantation, the body begins to produce more of the pregnancy hormones hCG ( human chorionic gonadotropin ) and progesterone . These hormones signal that the uterus is occupied, meaning that ovulation and menstruation will no longer take place. They also ensure that the uterine lining continues to be maintained and the embryo is supplied with a constant blood flow.

Symptoms of implantation

Some women feel little or nothing from the process of implantation. Others, however, are very aware of the change in their bodies. Possible signs of implantation may include the following:

Implantation bleeding: Often referred to as ‘spotting’, this light bleeding is usually harmless and disappears after a short time. It can occur when endometrial tissue is disrupted during the process of implantation.
Implantation pain: When the egg implants into the lining of the uterus, you may experience mild abdominal cramping, similar to menstrual cramps. This is commonly referred to as implantation cramps.

If implantation takes place, you may experience some of the following early pregnancy symptoms:

Tender breasts.
Altered sense of smell and taste
Discharge (cervical mucus)
Mood swings
Frequent urination
Abdominal bloating, constipation, and flatulence

If you experience these symptoms, you may be in the very early pregnancy stages. It may also be that you are experiencing premenstrual syndrome (PMS), as many of these symptoms overlap.

While you may want to take a pregnancy test right away, it is highly suggested to wait until two weeks after ovulation to take a pregnancy test . This is because hCG, the hormone detected in home pregnancy tests and blood tests at fertility clinics , takes some time to build up after implantation. By waiting two weeks, you have the best chance of avoiding a false negative or false positive pregnancy test result.

What can prevent fertilisation?

There are a number of factors that can prevent fertilisation; these may involve the male or female partner, or both. Some of the most common causes for fertilisation not happening are

Hormonal imbalances : Disturbed hormonal balance, such as in polycystic ovary syndrome (PCOS) , can interfere with fertilisation. PCOS causes irregular periods and increased testosterone levels, which can make ovulation and conception difficult. Hormonal imbalance in men can also lead to sperm production disorders.
Poor sperm quality: Low sperm count or low sperm quality can reduce the chances of successful fertilisation.
Blocked fallopian tubes: The fallopian tubes may be blocked, for example, due to adhesions after inflammation or adhesions, and therefore the sperm cannot reach the egg.
Age: Age can also be a factor that makes conception difficult. Women 35 and older tend to have fewer eggs, and egg quality decreases with age. The same is true for sperm quality.
Stress: Stress can affect hormones in both women and men, making successful fertilisation more difficult.
Lifestyle: Smoking, alcohol consumption, obesity and other unhealthy lifestyle habits can also have a negative impact on fertilisation.

What can prevent implantation of the fertilised egg?

Unfortunately, even after successful fertilisation, implantation may still not happen. Below are some causes that can complicate or prevent it:

Problems in the development of the embryo: It can happen that the female body recognises when an embryo is not viable and ends the pregnancy. For example, if there is a disorder of the chromosomes, it usually does not implant or may later result in a miscarriage ).
Hormonal disorders : These can make it difficult for the fertilised egg to implant, for example, by making the uterine lining thin or uneven. An inadequate uterine lining may prevent the egg from finding a suitable place to implant.
Infections : Infections of the lining of the uterus or cervix can interfere with implantation of the fertilised egg.
Ectopic pregnancy : this type of pregnancy is a rare complication in which the fertilised egg implants in the fallopian tube instead of the uterus. This can lead to dangerous complications because the fallopian tube does not provide enough space and nutrients for the embryo to develop.
Uterine malformations : Some women are born with uterine malformations that can interfere with implantation of the fertilised egg. These malformations may cause the uterus to be unevenly shaped or there may be a partition in the uterus that makes implantation difficult.
Immunologic factors : In some cases, the woman's immune system may prevent implantation of the fertilised egg. The immune system recognizes the embryo as a foreign object and attacks it before it has successfully implanted.

There are many different factors that can make fertilisation or implantation difficult. When couples or individuals remain involuntarily childless for a long period of time, it is a good idea to make an appointment with a doctor or fertility specialist. There are many reproductive medical treatments that can help increase the chances of successful conception, such as hormone therapies , intrauterine insemination (IUI) and in vitro fertilisation (IVF) .

How can I promote fertilisation and implantation?

Fertilisation of the female egg and subsequent implantation in the uterus are complex biological processes that depend on many factors. There is no special trick to influence them. However, there are things you can do to keep your body healthy and prepare it for pregnancy :

Eat a well-balanced diet . A healthy and balanced diet can help improve fertility. Supplements with folic acid can also be taken.
Regularly exercise . This can help reduce stress and regulate body weight, both of which are important factors in fertility.
Manage your stress. Stress can affect fertility, so it is important to find methods to manage stress. These include relaxation exercises such as yoga or meditation.
Avoid smoking, alcohol and other addictive substances. These can affect fertility and should be avoided.
Have sex at the right time. The best time to have sex is around ovulation if you are trying to get pregnant. You can determine your fertile window with an ovulation test or the temperature method, for example.
Maintain a healthy lifestyle. A healthy lifestyle and protecting yourself from harmful environmental factors can also positively influence fertility. This can include, for example, getting enough sleep or avoiding harmful substances, such as chemicals.

The process of conceiving a baby is highly complex. In order for fertilisation to occur, the female must ovulate a mature egg and the male must be able to ejaculate sperm that can travel down the female reproductive tract and penetrate the egg. Once the egg is fertilised, it can implant in the lining of the uterus, where it develops into an embryo and eventually a baby. A number of factors, such as proper timing of intercourse and partner fertility, are prerequisites for pregnancy to occur.

Unfortunately, the egg may have difficulty being fertilised or implanting due to a variety of causes. The reasons for this can be varied; for example, hormonal disorders, blocked fallopian tubes or infections can be responsible. If you are still involuntarily childless after a long period of trying, it may be a good idea to see a fertility specialist. There are many ways to get help and support for family planning.

Would you like support on your way to pregnancy? The Cada team is happy to guide you on your journey. Reserve your spot for a free consultation today.

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What to do after embryo transfer? – Recommendations

After an IVF embryo transfer (ET), achieving success depends exclusively on the embryos and their implantation potential. In spite of that, it is common for patients to ask themselves many questions, including what to do and what to avoid, if rest is necessary and to what extent, what are the precautions to be taken... In short, anything that may help to increase the chances for pregnancy .

Once the patient has left the transfer room, a completely different life from the one she had during the treatment begins: The embryo(s) have already been transferred, and here starts the countdown until the pregnancy test.

Provided below is an index with the 7 points we are going to expand on in this article.

1. Tips & precautions
2. Symptoms & positive signs
3. When to test for pregnancy
4. FAQs from users
4.1. Can I take a bath after the embryo transfer?
4.2. What precautions should I follow after embryo transfer in ICSI?
4.3. Are bloating, cramping and pain good signs after embryo transfer?
4.4. Is it necessary to rest after the transfer?
4.5. How long does it take for the embryo to implant after embryo transfer?
4.6. Is it normal to notice flu-like symptoms after embryo transfer?
4.7. I have zero symptoms but got a BFP, is that normal?
4.8. What should I eat after IVF embryo transfer?
4.9. When should I take a pregnancy test after a donor-egg embryo transfer?
4.10. What happens after embryo transfer on each day?
4.11. I'm feeling thrush symptoms after embryo transfer, what is the cause?
4.12. When is your period due if the embryo transfer doesn't work?
4.13. Can you fly right after IVF embryo transfer?
4.14. What is the best sleep position after embryo transfer?
4.15. How long after embryo transfer can you have intercourse?
4.16. Can smoking affect implantation after embryo transfer?
5. Suggested for you
6. References
7. Authors and contributors

Tips & precautions

There are many recommendations to follow after an embryo transfer. However, the most important thing for you to do is as simple as continuing with your normal lifestyle, trying not to become too obsessed with getting pregnant. To sum up, these are the most basic tips that every IVF patient should follow after an ET:

Imagen: How should I take care of myself after embryo transfer?

If medication is required due to any type of discomfort like headache, toothache, or any other infection alike, it is advisable to talk to the specialist who monitored the treatment. Either way, analgesic consumption is not a problem as long as it is paracetamol or any other similar painkiller.

Finally, it is important to have a positive attitude after the embryo transfer until the day of the pregnancy test. It is essential to avoid stress and anxiety and try to think about other things to reduce uncertainty during these days.

We recommend that you read the following article for further information on the subject: Should You Rest After Embryo Transfer in IVF?

Symptoms & positive signs

Symptoms vary from woman to woman, and even between pregnancies among women who have been pregnant before. Neither should you be concerned if no symptoms appear—it is not mandatory for every IVF patient to feel them. And most importantly, it does not translate into implantation failure by default.

The most common symptoms after embryo transfer can be caused by the beginning of a new pregnancy or by the fertility drugs you are taking. In other words, they do not indicate failure or success.

Some of the most common symptoms after embryo transfer, apart from the absence of menstruation , are the following:

Abundant vaginal discharge during the first days after the ET, due to elevated/altered hormonal levels and the vaginal administration of progesterone.
Spotting or mild bleeding caused by the passage of the catheter through the cervix; it often disappears within 2-3 days.
Breast changes caused by the exogenous administration of hormones before the transfer (estrogens and progesterone).
Fatigue as a side effect of your increased progesterone levels, which can be caused either by pregnancy or progesterone supplements.
Nausea and discomfort around the abdominal area, due to increased hormonal levels.
Frequent urination caused by rising hCG hormone levels, either caused by a new pregnancy or as an adverse reaction of hCG injections.

Imagen: Common symptoms after embryo transfer

The symptoms that we have just listed can appear irrespective of whether it was a Frozen Embryo Transfer (FET) or a fresh transfer, or if it was a day-3 or day-5 embryo.

It is advisable for you to contact the center that has been monitoring your treatment in case symptoms like bleeding, fever, vomits, swelling and abdominal pain, or even shortness of breath, show up.

If you need to undergo IVF to become a mother, we recommend that you generate your Fertility Report now. In 3 simple steps, it will show you a list of clinics that fit your preferences and meet our strict quality criteria. Moreover, you will receive a report via email with useful tips to visit a fertility clinic for the first time.

When to test for pregnancy

In natural pregnancies, the embryo attaches to the uterine lining about 6 to 8 days after entering the uterus. This means that embryo implantation occurs at blastocyst stage. In short, even though this is the precise moment when implantation takes place, the entire process can take up to one week to be fully completed.

In an IVF cycle, day-3 embryos should remain in the uterus at least for three more days until reaching blastocyst stage and being able to implant. However, day-5 embryos are already at blastocyst stage, which means that they are able to attach to the uterus immediately after the ET.

When to test for pregnancy after IVF embryo transfer

The only thing left to do to finish the unending wait is to do the pregnancy test. It is usually done 10-15 days following the date when the follicle puncture ( egg collection ) was performed. In case it was a Frozen Embryo Transfer (FET), it can be done within 10 days, counting from the stage of embryo development in which the embryo was at the moment of the ET.

It is totally unadvisable to do a pregnancy test earlier than indicated, since the pregnancy hormone (hCG) increases progressively. For this reason, if one takes the test too early, you may get a false negative result, as the levels of hCG are insufficient as to be detectable.

This test may be performed in two ways: in urine or in blood . To do this, the patient must follow the instructions facilitated by the fertility center. Irrespective of wether you get a positive or negative outcome, you should always communicate it to the clinic, so that the guidelines to follow from that moment on can be established.

In the event of the result being positive, it is highly possible that you are advised to make an appointment with your gynecologist to have a first ultrasound done and check that everything is right.

If the result is negative but there is no vaginal bleeding, it is very possible that you are recommended to repeat the test within one week, as after this time period it could turn into positive.

If your menstrual period shows up, it means that a new cycle has started, and that pregnancy has not occurred. In other words, that unfortunately your IVF embryo transfer has failed.

The most important thing to do now is to keep calm and follow step by step the guidelines established by your fertility clinic. Take into account that their goal is the same as yours.

FAQs from users

Can i take a bath after the embryo transfer.

Bathing in pools, spas, and tubs should be avoided for at least one week after the embryo transfer to avoid possible infection or interference with vaginal medication. There is no contraindication for daily showering.

What precautions should I follow after embryo transfer in ICSI?

The precautions to take after embryo transfer in ICSI are exactly the same as in any other infertility treatment: Avoiding stress, reducing the intake of caffeine or stopping it, avoiding vigorous exercises, abstaining from intercourse, not having hot baths, and staying positive above all.

Are bloating, cramping and pain good signs after embryo transfer?

Yes, these are considered to be normal symptoms after embryo transfer. As for pain, it is possible that, due to the stress generated during the treatment, the medications administered, and the manipulation of the uterus during the embryo transfer, the woman has headaches, stomachaches, or backaches.

If they range from mild to moderate intensity, there is no reason for you to be concerned. However, if it turns into an unbearable pain, we recommend that you visit your doctor.

Is it necessary to rest after the transfer?

No, it is not necessary to rest beyond the 30-40 minutes recommended by the specialist immediately after the transfer. As we have commented above, after this time, the woman can continue with her usual life, always avoiding excessive efforts.

How long does it take for the embryo to implant after embryo transfer?

As explained above, it takes more than one week for the embryo to implant since fertilization. To be precise, implantation takes place 6-8 days after the embryo enters the endometrial lining.

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Is it normal to notice flu-like symptoms after embryo transfer?

Experiencing cold-like symptoms and a stuffy nose is a common post embryo transfer symptom, actually. This phenomenon is commonly known as "IVF cold", and includes sneezing, nasal congestion and even coughing. As other symptoms, IVF colds are caused by changing hormone levels, whether you become pregnant or not. In fact, women taking birth control pills or undergoing hormone replacement therapy are likely to feel them too.

I have zero symptoms but got a BFP, is that normal?

Yes, symptoms are not an essential requirement for IVF to be successful. As explained earlier, it varies on a case-by-case basis. A woman not feeling common symptoms may get a positive pregnancy test (commonly referred to as BFP or Big Fat Positive ), while others noticing every symptom listed above may end up not being pregnant.

What should I eat after IVF embryo transfer?

In general, you should follow a healthy, balanced diet, avoiding junk food above all. Ideally, your diet should include a mix of fruits, protein- and carbohydrate-rich foods, vegetables, etc. Also, you should avoid taking caffeine. If you can't stop drinking caffeinated drinks, limit your intake to a maximum of 200 mg per day.

When should I take a pregnancy test after a donor-egg embryo transfer?

Like in any other IVF procedure, after an embryo transfer with donated eggs, women have to go through the two-week wait or 2WW, a time period necessary for beta-hCG levels to be detectable by a pregnancy test.

The presence of the hormone hCG in blood increases gradually from embryo implantation up until the end of the third trimester approximately. This, along with other hormonal changes, is the reason why the common pregnancy symptoms appear (nausea, vomiting, etc.)

What happens after embryo transfer on each day?

Supposing that the embryo continued to develop and that pregnancy occurred as expected, this is what one should expect from Day Post Transfer (DPT) 1 to 11 approximately:

The embryo turns from a 6-8 cell embryo to a morula
The cells of the morula continue dividing: the embryo reaches the blastocyst stage
Once a blastocyst, the embryo starts to hatch out of its "shell"
It begins to attach itself to the uterus
The implantation process continues: the embryo attaches deeper into the uterus
The implantation process continues
The embryo implantation process finishes and the cells that will form both the placenta and the fetus begin to develop
The production of hCG starts, and it begins to enter the bloodstream
Fetal development begins and hCG levels continue doubling
Fetal development continues and hCG levels continue increasing
hCG levels start now to be high enough to be detectable by pregnancy tests

I'm feeling thrush symptoms after embryo transfer, what is the cause?

In some cases, fertility specialists prescribe antibiotics prior to embryo transfer in order to prevent the presence of bacteria and other organisms to interfere with IVF outcomes. The use of antibiotics can cause women to develop candidiasis (vaginal yeast infection), as they can change the balance of those "good" microorganisms which help keep a healthy vaginal environment.

Nevertheless, there is no scientific proof that taking antibiotics improves the outcomes of IVF embryo transfers, so women who are prone to yeast infections should consider the use of antibiotics as just a preventive measure.

When is your period due if the embryo transfer doesn't work?

Firstly, if adequate hormone replacement therapy is given in the luteal phase, then your period should not show up until fertility medications are stopped. In general, your period should not appear earlier than 12 days after your ET.

Can you fly right after IVF embryo transfer?

Yes, there is no problem with that. Your embryos will be okay, floating freely inside your uterus. You can travel without being concerned about staying laying down, or your embryos falling out after transfer.

What is the best sleep position after embryo transfer?

Actually, you can choose the sleep position that is most comfortable for you. It's just as simple as that. There is no recommended sleep position, or a position that is unadvisable.

In fact, the common belief that bed rest is necessary after an ET is a myth that can be counterproductive, as it increases the levels of stress in the woman. It is erroneous to think that gravity can make the embryos fall out or reduce their possibilities of implanting.

How long after embryo transfer can you have intercourse?

It depends on a case-by-case basis, so you better follow your doctor's instructions. Anyway, pelvic rest may be recommended anywhere from 5 to 15 days after the embryo transfer.

Can smoking affect implantation after embryo transfer?

Smoking tobacco can affect the proper growth of the embryo—and fetal development in case pregnancy occurs. Moreover, it can reduce your fertility and reduce your chances of getting pregnant. For this reason, we strongly recommend that all IVF patients stop smoking before, during, and after their infertility treatment at once.

Suggested for you

This post is a summary of the general tips and symptoms that you are likely to feel after an IVF embryo transfer procedure. However, if you want to delve deeper into the most common symptoms after an ET, we recommend that you go visit this complete guide: Symptoms After Embryo Transfer: Most Common Positive Signs .

If the two-week wait has already come to its end for you, and you found out that you are pregnant... Congratulations! But now, what's next? To learn more about the signs and symptoms often associated with embryo implantation, check this out: What Are the First Signs & Symptoms of Embryo Implantation?

Finally, we have made references to day-3 and day-5 embryo transfers, and the main difference between them when it comes to determining the moment of embryo implantation. Want to get more details about the differences between them? Get answers here: Embryo Transfer on Day 3 or on Day 5?

We make a great effort to provide you with the highest quality information.

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Amarin ZO, Obeidat BR. Bed rest versus free mobilisation following embryo transfer: a prospective randomised study. BJOG. 2004 Nov;111(11):1273-6 ( View )

Cozzolino M, Troiano G, Esencan E. Bed rest after an embryo transfer: a systematic review and meta-analysis. Arch Gynecol Obstet. 2019 Nov;300(5):1121-1130 ( View )

Gaikwad S, Garrido N, Cobo A, Pellicer A, Remohi J. Bed rest after embryo transfer negatively affects in vitro fertilization: a randomized controlled clinical trial. Fertil Steril. 2013 Sep;100(3):729-35 ( View )

Purcell KJ, Schembri M, Telles TL, Fujimoto VY, Cedars MI. Bed rest after embryo transfer: a randomized controlled trial. Fertil Steril. 2007 Jun;87(6):1322-6 ( View )

FAQs from users: 'Can I take a bath after the embryo transfer?' , 'What precautions should I follow after embryo transfer in ICSI?' , 'Are bloating, cramping and pain good signs after embryo transfer?' , 'Is it necessary to rest after the transfer?' , 'How long does it take for the embryo to implant after embryo transfer?' , 'Is it normal to notice flu-like symptoms after embryo transfer?' , 'I have zero symptoms but got a BFP, is that normal?' , 'What should I eat after IVF embryo transfer?' , 'When should I take a pregnancy test after a donor-egg embryo transfer?' , 'What happens after embryo transfer on each day?' , 'I'm feeling thrush symptoms after embryo transfer, what is the cause?' , 'When is your period due if the embryo transfer doesn't work?' , 'Can you fly right after IVF embryo transfer?' , 'What is the best sleep position after embryo transfer?' , 'How long after embryo transfer can you have intercourse?' and 'Can smoking affect implantation after embryo transfer?' .

Authors and contributors

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Hi, my wife she had her embryos transferred today and after almost 6 hours she started vomiting, is that ok? I am a bit worried. Pls tell me something soon. Thanks.

Hello Sana,

Yes, that is a normal symptom after embryo transfer. It is caused by the medications she’s been taking, and because of the transfer itself, but it does not mean the treatment has failed.

Just keep calm during the 2ww 😉

Hey gurls, I’m on my 3rd day post transfer, 2 beautiful embryos (day 3). It was my first IVF attempt due to bilateral hydrosalpinx… I’ve read it’s very complicated for a person with hydrosalpinx to become pregnant… I’m on the 2ww and freaking out!!! If I succeed, it will be my 1st baby and to be honest I thought I would never make it due to the hydrosalpinx, but support from my partner has been material for be to be where I am at this moment!! No words can describe how grateful I am… fyi, I’ve had no symptoms except for a very mild pain on my ovaries… Is it normal?

Dear Kylie,

I’m sorry to tell you that a natural pregnancy is not possible with bilateral hydrosalpinx. However, these patients are able to become mothers thanks to IVF, as it is your case.

Moreover, performing a tubal occlusion procedure before starting the treatment can be highly beneficial to prevent the fluid in your fallopian tubes to spread and become toxic for the embryos. I don’t know if you have had it already done or not.

Wishing you lots of luck.

Thanks for this beautiful answer. Actually I was worried, but you have calmed down my nerves.

Tomorrow will be 2 weeks since my transfer!!! Bloodwork in the morning and results in the afternoon. That will feel longer than the 2 weeks we had to wait!!!

Hi, I had a single, 5day embryo transfer done last Monday, 14th June. I had no symptoms and no brown bleeding. But this morning I woke up with nipple pain but not breast pain, and my legs are like tired or organism pain. What could really cause it? Could I be pregnant?

I’m 1dp5dt with an average blasto. This is our 2nd cycle and our embryo quality was nowhere near what we got on cycle 1; which thankfully we have x3 top graders on!!

I’ve been feeling AF symptoms before transfer and even more so now. Throbbing pain down my right thigh, lower back ache, sore boobs & those mood swings! However I’ve been having a burning sensation on the left side of my abdomen. Never experienced that before!!

The 2ww is exhausting no matter how many words of encouragement. Just wish there was a way to look inside the womb during this time… Fingers & toes crossed this cycle works. Baby dust to all mummy’s-to-be x

I just had 2 embryos transferred last Tuesday 7th June. Until now, I feel good except sometimes some very slight pain in the ovaries area. Do I understand that everything is ok? Or there are some symptoms that should appear so that it shows that I`m pregnant?

Every lady is different and most likely things are going well for you and your embryos! Side effects from the pesky pessaries don’t help neither (that’s if you get the symptoms) but not long now before you can test. Best of luck to you.

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Is it safe to travel by a two or three wheeler during pregnancy?

Riding a two wheeler in pregnancy

Travelling by auto or rikshaw in pregnancy.

Three-wheeled vehicles have less stability and balance than four-wheeled ones.
They don't have basic safety features such as a seat belt, suspension, an airbag etc.
They are open and so leave you more vulnerable to injury if they topple over or from flying debris.
They travel on the same roads as cars, trucks and busses that go much faster and have a much stronger build. Even a minor collision with any of these other kinds of vehicles would damage the auto or rikshaw proportionately more, leaving you more vulnerable to injury.
Ask the driver before you get in to drive slowly and carefully. If you feel comfortable with it, you can even tell him you're expecting so that he takes you seriously.
Try to use autos and rikshaws only for short trips.
If possible, plan your outing outside of peak traffic times to avoid chaotic roads that make travelling more dangerous.
Use a face mask to protect yourself from the pollution, dust and unpleasant smells that might trigger nausea .
Carry water, especially in hot weather when warm winds can make you dehydrated quickly.
Hold on tight to the handlebars.

Alternatives to two and three wheel transportation in pregnancy

Arrange a car pool. Whether it's to drop an older child to school, or to go to office yourself, car pools can be very useful.
Use public transport. With more modern busses and metros coming up in most big cities, public transport is a good option and much safer for daily commutes.
Rely more on home deliveries where possible to reduce your need to go out.
Check with your office if you can work from home for a few days a week.
See if you can share a cab with colleagues.
Can a bumpy road bring on labour?
Pregnancy travel: where to go and how to decide
How to tell your employer you're expecting

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Travelling by car during pregnancy

Travelling by train during pregnancy

Indian woman looking out of train window

Tips for safely using public bathrooms in pregnancy

Is it safe to travel to high altitudes or hot destinations during pregnancy?

BabyCenter's editorial team is committed to providing the most helpful and trustworthy pregnancy and parenting information in the world. When creating and updating content, we rely on credible sources: respected health organisations, professional groups of doctors and other experts, and published studies in peer-reviewed journals. We believe you should always know the source of the information you're seeing. Learn more about our editorial and medical review policies .

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Solar eclipse 2024: Here's why you don't want to be on the road during April 8 eclipse

We know you've heard this many times, but it must be said often and strongly: do not look at the sun on april 8 (or any other day, for that matter) without certified glasses..

Editor's note: The information below was taken from a longer column written by Dr. David Rogers, Dr. Julia Stokes, Dr. Ryan Squier and Dr. Aaron Zimmerman and submitted by the Central Ohio Hospital Council . Find that column here .

Driving during the April 8 solar eclipse is expected to come with unique risk.

It’s not a concern that most people think of, but Ohio’s expecting an influx of between 100,000 and 500,000 visitors from other states on April 8. They, and thousands of citizens from southern and eastern parts of our state, are expected to converge on the areas that will experience partial and total darkness.

States in the path of past solar eclipses saw major traffic congestion and more than the usual number of traffic accidents and distracted-driver incidents in the days before, during and after the event. In Ohio counties where the eclipse will be viewable, public officials and hospital emergency departments, including ours in Franklin County (in partial totality), are preparing for the same.

Spectacular and dangerous. How to safely enjoy 2024 solar eclipse.

If you’re in one of the full or partial totality counties (see the map on the Ohio Emergency Management website; link below), our advice is to stay home between noon and 5 p.m. on April 8.

Run your errands early in the day or, better yet, in the days before. Traffic in totality areas – even partial totality – will be busy, and drivers will be distracted, especially between 3 p.m. and 4 p.m. on April 8.

If you plan to drive to an event, plan to arrive early and stay late to reduce your time sitting in traffic. Don’t wear eclipse glasses while driving; you can’t see much while wearing them.

That’s a good thing when looking at the sun; not so for driving and other activities.

Stay alert in crowds on eclipse day

There are many large gatherings planned in central Ohio and throughout the state on eclipse day.

If you’ll be at one, keep a close eye on children and pets and be sure they have identification on them. This will be at least a 3-or-4-hour event. Arrive early and take enough sunscreen, bug spray, water and snacks. Dress for the weather.

If it’s a private event, watch out for people drinking alcohol or using mind-altering substances. Their judgment will be impaired, and they may attempt risky behavior, including staring at the sun without protection.

There will be a lot of down time over the length of the eclipse, so plan how you’ll occupy your time, and know that you won’t be wearing your ISO-certified glasses every minute. Keep this in mind, if you too plan to partake.

As health professionals, we advise you not to, especially if you’re with children.

Solar eclipse 2024 in Ohio: Best places to be dazzled by the sun April 8

As for us, we’re planning to experience this event with family, friends, or co-workers, and we have our viewing glasses ready. Several of us have seen total solar eclipses in other parts of the country, and they were amazing.

Like touching boiling water. April 8 solar eclipse can leave you blind or without color

If you can’t get outside to see it, or you would rather watch it in the comfort of your home, tune in to NASA’s live telecast online at plus.nasa.gov starting at 1 p.m. April 8.

We hope you enjoy every minute, and we wish all of you clear skies on April 8.

Where to find more information

Ohio Emergency Management : ema.ohio.gov . Ohio’s main information and reference website for the 2024 eclipse. Learn about the path of the eclipse through Ohio, get safety and planning advice, as well as links to other organizations involved in eclipse activities, parking dos and don’ts, and more.
American Astronomical Society: Find numerous features here, including a list of approved vendors for eclipse glasses on the Eye Safety page. Remember, these glasses are absolutely necessary if you look directly at the sun. Get yours free at a local library or order them from a reputable vendor now! Don’t delay. See eclipse.aas.org/eclipse-america-2024
NASA Plus Live Telecast : If it’s cloudy where you are, or you can’t get outside, watch the eclipse online thanks to NASA satellites and land centers. Watch at plus.nasa.gov starting at 1 p.m.

Dr. David Rogers is chief of Nationwide Children’s Hospital's Department of Pediatric Ophthalmology. Dr. Julia Stokes is a Mount Carmel Medical Group Grove City Family Health family practice physician. Dr. Ryan Squier is associate medical director at the OhioHealth New Albany Emergency Department. Dr. Aaron Zimmerman is a clinical professor at the Ohio State University College of Optometry .

Total solar eclipse April 8, 2024 facts: Path, time and the best places to view

In the U.S., 31 million people already live inside the path of totality.

Scroll down to see the list of U.S. cities where the April 8 total solar eclipse will be visible, the duration of the eclipse in those locations and what time totality will begin, according to GreatAmericanEclipse.com .

"Eclipse Across America," will air live Monday, April 8, beginning at 2 p.m. ET on ABC, ABC News Live, National Geographic Channel, Nat Geo WILD, Disney+ and Hulu as well as network social media platforms.

On April 8, 2024, a historic total solar eclipse will cast a shadow over parts of the United States, prompting a mass travel event to the path of totality -- from Texas to Maine and several states and cities in between.

A total solar eclipse occurs when the moon passes between the sun and the Earth and, for a short time, completely blocks the face of the sun, according to NASA .

PHOTO: Tyler Hanson, of Fort Rucker, Ala., watches the sun moments before the total eclipse, Aug. 21, 2017, in Nashville, Tenn.

The track of the moon's shadow across Earth's surface is called the path of totality, and to witness the April 8 total solar eclipse, viewers must be within the 115-mile-wide path. To discover when to see the solar eclipse in totality or the partial eclipse in locations across the U.S. outside of the path, check out NASA's Eclipse Explorer tool .

Eclipse travel

In the U.S., 31 million people already live inside the path of totality, bringing the celestial phenomenon to their doorsteps, Michael Zeiler, expert solar eclipse cartographer at GreatAmericanEclipse.com told ABC News.

MORE: Eclipse glasses: What to know to keep your eyes safe

But for individuals outside of the path, investing time and money are needed to experience the event in totality.

PHOTO: People watch a partial solar eclipse from the roof deck at the 1 Hotel Brooklyn Bridge on Aug. 21, 2017 in the Brooklyn borough of New York City.

Eclipse chasers, or umbraphiles, are individuals who will do almost anything, and travel almost anywhere, to see totality, according to the American Astronomical Society .

"There's a very active community of solar eclipse chasers and we will go to any reasonable lengths to see solar eclipses anywhere in the world," Zeiler said. "All of us are united in pursuing the unimaginable beauty of a total solar eclipse."

MORE: The surprising reason why a Texas county issued a disaster declaration ahead of April total solar eclipse

Bringing together both eclipse experts and novice sky watchers, the total solar eclipse on April 8 is projected to be the U.S.'s largest mass travel event in 2024, according to Zeiler, who likened it to "50 simultaneous Super Bowls across the nation."

"When you look at the number of people expected to come to the path of totality for the solar eclipse, we estimate those numbers are roughly the equivalent of 50 simultaneous Super Bowls across the nation, from Texas to Maine," he said.

Eclipse map, path of totality

In the U.S., the path of totality begins in Texas and will travel through Oklahoma, Arkansas, Missouri, Illinois, Kentucky, Indiana, Ohio, Pennsylvania, New York, Vermont, New Hampshire and Maine. Small parts of Tennessee and Michigan will also experience the total solar eclipse, according to NASA.

Best times, places to view eclipse

Below is a list of some American cities where the April 8 total solar eclipse will be most visible -- pending weather forecasts -- the duration of the eclipse in those locations and what time totality will begin, according to GreatAmericanEclipse.com.

Eagle Pass, Texas, 1:27 p.m. CDT: 4 minutes, 23 seconds
Uvalde, Texas, 1:29 p.m. CDT: 4 minutes, 16 seconds
Kerrville, Texas, 1:32 p.m. CDT: 4 minutes, 23 seconds
Austin, Texas, 1:36 p.m. CDT: 1 minute, 53 seconds
Killeen, Texas, 1:36 p.m. CDT: 4 minutes, 17 seconds
Fort Worth, Texas, 1:40 p.m. CDT: 2 minutes, 34 seconds
Dallas, Texas, 1:40 p.m. CDT: 3 minutes, 47 seconds
Little Rock, Arkansas, 1:51 p.m. CDT: 2 minutes, 33 seconds
Jonesboro, Arkansas, 1:55 p.m. CDT: 2 minutes, 24 seconds
Poplar Bluff, Arkansas, 1:56 p.m. CDT: 4 minutes, 8 seconds
Cape Girardeau, Missouri, 1:58 p.m. CDT: 4 minutes, 6 seconds
Carbondale, Illinois, 1:59 p.m. CDT: 4 minutes, 8 seconds
Mount Vernon, Illinois, 2:00 p.m. CDT: 3 minutes, 40 seconds
Evansville, Indiana, 2:02 p.m. CDT: 3 minutes, 2 seconds
Terre Haute, Indiana, 3:04 p.m. EDT: 2 minutes, 57 seconds
Indianapolis, Indiana, 3:06 p.m. EDT: 3 minutes, 46 seconds
Dayton, Ohio, 3:09 p.m. EDT: 2 minutes, 46 seconds
Wapakoneta, Ohio, 3:09 p.m. EDT: 3 minutes, 55 seconds
Toledo, Ohio, 3:12 p.m. EDT: 1 minute, 54 seconds
Cleveland, Ohio, 3:13 p.m. EDT: 3 minutes, 50 seconds

Pennsylvania

Erie, Pennsylvania, 3:16 p.m. EDT: 3 minutes, 43 seconds
Buffalo, New York, 3:18 p.m. EDT: 3 minutes, 45 seconds
Rochester, New York, 3:20 p.m. EDT: 3 minutes, 40 seconds
Syracuse, New York, 3:23 p.m. EDT: 1 minute, 26 seconds
Burlington, Vermont, 3:26 p.m. EDT: 3 minutes, 14 seconds
Island Falls, Maine, 3:31 p.m. EDT: 3 minutes, 20 seconds
Presque Island, Maine, 3:32 p.m. EDT: 2 minutes, 47 seconds

Why April’s total solar eclipse will be historic

April total solar eclipse: Where to avoid clouds

Apr 1, 5:02 AM

Total solar eclipse weather forecast on April 8

Apr 3, 11:12 AM

April 8 partial solar eclipse times and magnitudes

Apr 4, 6:31 AM

How the eclipse will deliver a 'tourism boom'

Apr 4, 5:01 AM

ABC News Live

24/7 coverage of breaking news and live events

Can I travel during implantation days?

FAQs about traveling during implantation days:

1. can travel affect the chances of successful implantation, 2. are there any specific precautions i should take while traveling during the implantation phase, 3. can flying affect implantation, 4. are there any travel restrictions during the implantation phase, 5. can stress from travel affect implantation, 6. when should i inform the airline or accommodation provider about my pregnancy, 7. what if i experience spotting or cramping while traveling, 8. should i avoid strenuous activities or long walks during travel, 9. are there any specific dietary recommendations while traveling during implantation, 10. can i travel by car while experiencing implantation, 11. how soon after implantation can i take a pregnancy test, 12. what if i need medical assistance during my travel.

Yes, you can generally travel during implantation days, as it is a very early stage of pregnancy and unlikely to have any major impact on your ability to travel. Implantation occurs when a fertilized egg attaches itself to the lining of the uterus, typically around 6-12 days after conception. During this time, there may be some mild spotting or cramping as the embryo burrows into the uterine wall. However, these symptoms are usually very mild and should not interfere with your travel plans.

It is important to note that every woman’s body and pregnancy journey is unique, so it’s always a good idea to consult with your healthcare provider before making any travel plans. They can provide personalized advice based on your individual circumstances and health history. In certain cases, such as high-risk pregnancies or complications, your healthcare provider may advise against extensive travel or suggest certain precautions to take during the journey.

Traveling itself does not have a direct impact on the chances of successful implantation. Implantation depends more on factors like the health of the embryo and the receptivity of the uterus. However, it’s always a good idea to maintain a healthy lifestyle, including regular exercise and a balanced diet, which may indirectly support the implantation process.

While traveling during implantation, it’s important to prioritize your comfort and well-being. Make sure to stay hydrated by drinking plenty of water and avoid prolonged periods of sitting or standing. If you are flying, try to walk around the cabin or do some light stretching exercises to improve blood circulation. Additionally, it’s recommended to wear loose-fitting and comfortable clothing to avoid any unnecessary pressure on your abdomen.

Flying itself is unlikely to have a direct impact on implantation. The cabin pressure and altitude changes during a flight are generally well-tolerated by most individuals, including pregnant women. However, it’s always advisable to check with your healthcare provider, especially if you have any pre-existing medical conditions or a history of complications.

In most cases, there are no specific travel restrictions during the implantation phase. However, it’s important to consider the destination and the potential risks associated with the location. If you are traveling to a region with a high prevalence of infectious diseases, it’s advisable to consult with your healthcare provider for any necessary vaccinations or precautions.

While stress does not directly cause implantation failure, excessive stress levels can have an impact on your overall well-being and potentially affect hormonal balance. It’s important to minimize stress as much as possible, especially during the implantation phase. Engaging in relaxation techniques, such as deep breathing exercises, meditation, or listening to calming music, can help manage stress levels during your travel.

It’s generally not necessary to inform the airline or accommodation provider about your pregnancy during the implantation phase. However, if you are experiencing any complications or have concerns, it’s always a good idea to notify them in advance to ensure they can accommodate your needs and provide necessary support if required.

Spotting or mild cramping during the implantation phase is considered normal. However, if you experience excessive bleeding, severe pain, or any other concerning symptoms, it’s essential to seek immediate medical attention. Carry the contact information of a local hospital or healthcare provider at your destination for any emergencies.

Engaging in simple, light activities like walking is generally safe during the implantation phase. However, it’s important to listen to your body and avoid overexertion. If you feel tired or uncomfortable, take breaks, and rest as needed. It’s always a good idea to strike a balance between staying active and giving your body the rest it needs during the early stages of pregnancy.

There are no specific dietary restrictions during the implantation phase, but it’s important to maintain a healthy and balanced diet. Focus on consuming nutritious foods and staying hydrated. Pack healthy snacks for your journey and try to avoid excessive consumption of caffeine or alcohol. If you have any dietary restrictions or concerns, consult with your healthcare provider for personalized advice.

Traveling by car is generally safe during implantation, as long as you take necessary precautions. Make sure to wear your seatbelt correctly, take breaks for stretching and walking every few hours, and maintain proper posture while seated to avoid any discomfort. Consider planning your journey with frequent rest stops and overnight stays if needed to ensure adequate rest and relaxation during your travel.

Pregnancy tests generally detect the presence of the pregnancy hormone hCG (human chorionic gonadotropin) in the urine or blood. While it varies for each woman, hCG levels typically rise in the days after implantation. It’s advisable to wait at least a week after implantation to take a home pregnancy test for more accurate results. However, consulting with your healthcare provider can provide further guidance on the appropriate timing for testing.

If you require medical assistance during your travel, contact the local authorities or medical services at your destination immediately. It’s a good idea to have travel insurance that covers medical emergencies to provide financial security in case of unexpected healthcare needs. If you have any pre-existing medical conditions, it may be beneficial to carry a summary of your medical history, prescriptions, and contact details of your healthcare provider.

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A Danish frigate deployed to the Red Sea as part of a U.S.-led operation suffered malfunctioning of its weapon systems when attacked by drones operated by Houthi militants last month, the captain said on Thursday as the ship arrived in Denmark.

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Strong Taiwan Quake Kills 9, Injures Hundreds

The earthquake was the most powerful to hit the island in 25 years. Dozens of people remained trapped, and many buildings were damaged, with the worst centered in the city of Hualien.

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Hualien, Taiwan A landslide after the quake. Lam Yik Fei for The New York Times
New Taipei City, Taiwan Books flew off shelves as a home shook. @Abalamindo via Storyful
Taipei, Taiwan Passengers waiting at a train station as some services were suspended. Chiang Ying-Ying/Associated Press
Hualien, Taiwan People are rescued from a building that had partially collapsed. TVBS via Associated Press
Hualien, Taiwan Firefighters rescuing trapped residents from a building. CTI News via Reuters
Taipei, Taiwan Students evacuated to a school courtyard after the earthquake. Lam Yik Fei for The New York Times
Guishan Island, Taiwan Rocks tumbling down one side of an island popular for hiking. Lavine Lin via Reuters
Hualien, Taiwan A building leaned to one side after the quake. Randy Yang via Associated Press
Ishigaki, Okinawa, Japan Watching news on a rooftop of a hotel after a tsunami warning. Chang W. Lee/The New York Times
Hualien, Taiwan Motorbikes damaged in the quake. TVBS via Associated Press
New Taipei City, Taiwan Damage in an apartment Fabian Hamacher/Reuters
New Taipei City, Taiwan Water cascading down a building during the quake. Wang via Reuters

Meaghan Tobin and Victoria Kim

Here’s what you need to know about the earthquake.

Taiwan was rocked Wednesday morning by the island’s strongest earthquake in a quarter century, a magnitude 7.4 tremor that killed at least nine people, injured more than 800 others and trapped dozens of people.

The heaviest damage was in Hualien County on the island’s east coast, a sleepy, scenic area prone to earthquakes. Footage from the aftermath showed a 10-story building there partially collapsed and leaning heavily to one side, from which residents emerged through windows and climbed down ladders, assisted by rescuers. Three hikers were killed after being hit by falling rocks on a hiking trail in Taroko National Park, according to the county government.

By late afternoon, officials said rescue efforts were underway to try to rescue 127 people who were trapped, many of them on hiking trails in Hualien.

One building in Changhua County, on the island’s west coast, collapsed entirely. The quake was felt throughout Taiwan and set off at least nine landslides, sending rocks tumbling onto Suhua Highway in Hualien, according to local media reports. Rail services were halted at one point across the island.

The earthquake, with an epicenter off Taiwan’s east coast, struck during the morning commute, shortly before 8 a.m. Taiwanese authorities said by 3 p.m., more than 100 aftershocks, many of them stronger than magnitude 5, had rumbled through the area.

In the capital, Taipei, buildings shook for over a minute from the initial quake. Taiwan is at the intersection of the Philippine Sea tectonic plate and the Eurasian plate, making it vulnerable to seismic activity. Hualien sits on multiple active faults, and 17 people died in a quake there in 2018.

Here is the latest:

The earthquake hit Taiwan as many people there were preparing to travel for Tomb Sweeping Day, a holiday across the Chinese-speaking world when people mourn the dead and make offerings at their graves. Officials warned the public to stay away from visiting tombs in mountain areas as a precaution, especially because rain was forecast in the coming days.

TSMC, the world’s biggest maker of advanced semiconductors, briefly evacuated workers from its factories but said a few hours later that they were returning to work. Chip production is highly precise, and even short shutdowns can cost millions of dollars.

Christopher Buckley

Lai Ching-te, Taiwan’s vice president, who is also its president-elect, visited the city of Hualien this afternoon to assess the destruction and the rescue efforts, a government announcement said. Mr. Lai, who will become president in May, said the most urgent tasks were rescuing trapped residents and providing medical care. Next, Mr. Lai said, public services must be restored, including transportation, water and power. He said Taiwan Railway’s eastern line could be reopened by Thursday night.

Meaghan Tobin

Taiwan’s fire department has updated its figures, reporting that nine people have died and 934 others have been injured in the quake. Fifty-six people in Hualien County remain trapped.

Shake intensity

Taiwan’s fire department reports that nine people have died and 882 others have been injured in Taiwan. In Hualien County, 131 people remain trapped.

Agnes Chang

Footage shows rocks tumbling down one side of Guishan Island, a popular spot for hiking known as Turtle Island, off the northeast coast of Taiwan. Officials said no fishermen or tourists were injured after the landslide.

The death toll has risen to nine, according to Taiwan government statistics.

Meaghan Tobin, Siyi Zhao

Officials in Taiwan warned residents to not visit their relatives' tombs, especially in the mountains, this weekend during the holiday, known as Ching Ming, meant to honor them. There had already been 100 aftershocks and the forecast called for rain, which could make travel conditions on damaged roads more treacherous.

Crews are working to reach people trapped on blocked roads. As of 1 p.m. local time, roads were impassable due to damage and fallen rock in 19 places, according to the Ministry of Transportation. At least 77 people remain trapped. A bridge before Daqingshui Tunnel appeared to have completely collapsed.

Taiwan’s worst rail disaster in decades — a train derailment in 2021 that killed 49 people — took place on the first day of the Tomb Sweeping holiday period that year, in the same region as the earthquake.

The earthquake hit Taiwan as many people here were preparing to travel for Tomb Sweeping Day, or Ching Ming, a day across the Chinese-speaking world when people mourn their dead, especially by making offerings at their graves. Now those plans will be disrupted for many Taiwanese.

The holiday weekend would typically see a spike in travel as people visit family across Taiwan. Currently, both rail transport and highways are blocked in parts of Hualien, said Transport Minister Wang Guo-cai. Work is underway to restore rail transportation in Hualien, and two-way traffic is expected to be restored at noon on Thursday, he said.

Taiwan’s preparedness has evolved in response to past quakes.

Taiwan’s earthquake preparedness has evolved over the past few decades in response to some of the island’s largest and most destructive quakes .

In the years after a 7.6 magnitude earthquake in central Taiwan killed nearly 2,500 people in 1999, the authorities established an urban search-and-rescue team and opened several emergency medical operation centers, among other measures .

And in 2018, after a quake in the eastern coastal city of Hualien killed 17 people and caused several buildings to partially collapse, the government ordered a wave of building inspections .

Taiwan has also been improving its early warning system for earthquakes since the 1980s. And two years ago, it rolled out new building codes that, among other things, require owners of vulnerable buildings to install ad-hoc structural reinforcements.

So how well prepared was Taiwan when a 7.4 magnitude quake struck near Hualien on Wednesday morning, killing at least seven people and injuring hundreds more?

Across the island, one building collapsed entirely, 15 others were in a state of partial collapse and another 67 were damaged, the island’s fire department said on Wednesday afternoon . Structural engineers could not immediately be reached for comment to assess that damage, or the extent to which building codes and other regulations might have either contributed to it or prevented worse destruction.

As for search-and-rescue preparedness, Taiwan is generally in very good shape, said Steve Glassey, an expert in disaster response who lives in New Zealand.

“ The skill sets, the capabilities, the equipment, the training is second to none,” said Dr. Glassey, who worked with Taipei’s urban search-and-rescue team during the response to a devastating 2011 earthquake in Christchurch, New Zealand. “They’re a very sharp operation.”

But even the best urban search-and-rescue team will be stretched thin if an earthquake causes multiple buildings to collapse, Dr. Glassey said.

Taiwan has options for requesting international help with search-and-rescue efforts. It could directly ask another country, or countries, to send personnel. And if multiple teams were to get involved, it could ask the United Nations to help coordinate them, as it did after the 1999 earthquake.

Pierre Peron, a spokesman for the United Nations, said on Wednesday afternoon that no such request had yet been made as a result of the latest earthquake.

Meaghan Tobin contributed reporting.

At least seven people have died and 736 have been injured as a result of the earthquake, according to Taiwan’s fire department. Another 77 people remained trapped in Hualien County, many of them on hiking trails. Search and rescue operations are underway, said the fire department.

Aftershocks of magnitudes between 6.5 and 7 were likely to occur over the next three or four days, said Wu Chien-fu, director of the Taiwanese Central Weather Administration’s Seismology Center, at a news conference.

As of 2 p.m., 711 people had been injured across Taiwan, the fire department said, and 77 people in Hualien County remained trapped. The four who were known to have died were in Hualien.

Victoria Kim

Hualien County is a quiet and scenic tourist destination.

Hualien County on Taiwan’s east coast is a scenic, sleepy tourist area tucked away from the island’s urban centers, with a famous gorge and aquamarine waters. It also happens to sit on several active faults , making it prone to earthquakes.

The county has a population of about 300,000, according to the 2020 census, about a third of whom live in the coastal city of Hualien, the county seat. It is one of the most sparsely populated parts of Taiwan. About three hours by train from the capital, Taipei, the city describes itself as the first place on the island that’s touched by the sun.

Hualien County is home to Taroko National Park, one of Taiwan’s most popular scenic areas. Visitors come to explore the Taroko Gorge, a striated marble canyon carved by the Liwu River, which cuts through mountains that rise steeply from the coast. The city of Hualien is a popular destination as a gateway to the national park.

According to the state-owned Central News Agency, three hikers were trapped on a trail near the entrance to the gorge on Wednesday, after the quake sent rocks falling. Two of them were found dead, the news agency said. Administrators said many roads within the park had been cut off by the earthquake, potentially trapping hikers, according to the report.

Earthquakes have rattled Hualien with some regularity. In 2018, 17 people were killed and hundreds of others injured when a magnitude 6.5 quake struck just before midnight, its epicenter a short distance northeast of the city of Hualien.

Many of the victims in that quake were in a 12-story building that was severely tilted, the first four floors of which were largely crushed, according to news reports from the time. The next year, the area was shaken by a 6.1-magnitude earthquake that injured 17 people.

The area has some of the highest concentrations of Taiwan’s aboriginal population, with several of the island’s Indigenous tribes calling the county home .

The county government in Hualien released a list of people that had been hospitalized with injuries, which stood at 118 people as of midday Wednesday.

Across Taiwan, one building fell down entirely, in Changhua County on the west coast, and 15 buildings partially collapsed, Taiwan’s fire department said. Another 67 buildings were damaged. One of the partially collapsed structures was a warehouse in New Taipei City where four people were rescued, according to Taiwan’s Central News Agency. Another 12 were rescued at a separate New Taipei City building where the foundation sank into the ground.

Peggy Jiang, who manages The Good Kid, a children’s bookstore down the street from the partially collapsed Uranus Building in Hualien, said it was a good thing they had yet to open when the quake struck. The area is now blocked off by police and rescue vehicles. “Most people in Hualien are used to earthquakes,” she said. “But this one was particularly scary, many people ran in the street immediately afterward.”

Lin Jung, 36, who manages a shop selling sneakers in Hualien, said he had been at home getting ready to take his 16-month-old baby to a medical appointment when the earthquake struck. He said it felt at first like a series of small shocks, then “suddenly it turned to an intense earthquake shaking up and down.” The glass cover of a ceiling lamp fell and shattered. “All I could do was protect my baby.”

Chris Buckley , Paul Mozur , Meaghan Tobin and John Yoon

The earthquake damaged buildings and a highway in Hualien.

The magnitude 7.4 earthquake that struck Taiwan on Wednesday damaged many buildings and a major highway in Hualien, a city on the eastern coast, and it knocked out power as it rocked the island.

Across Taiwan, the quake and its aftershocks caused one building to completely collapse and 15 others to partially collapse, according to Taiwan’s fire department. Sixty-seven other buildings sustained damage.

Two tall buildings in Hualien that sustained particularly extensive damage were at the center of the rescue efforts there. Most damage across the city was not life-threatening, said Huang Hsuan-wan, a reporter for a local news site.

Where buildings were reported damaged in Hualien City

“A lot of roads were blocked off. There are a lot of walls toppled over onto cars,” Derik du Plessis, 44, a South African resident of Hualien, said shortly after the earthquake. He described people rushing around the city to check on their houses and pick up their children. One of his friends lost her house, he said.

One of the damaged buildings in Hualien, a 10-story structure called the Uranus Building that housed a mix of homes and shops, was tilted over and appeared to be on the verge of collapse. Many of its residents managed to flee, but some were missing, said Sunny Wang, a journalist based in the city. Rescuers were trying to reach the basement, concerned that people might be trapped there.

Photographs of the initial damage in Hualien showed another building, a five-story structure, leaning to one side, with crushed motorcycles visible at the ground-floor level. Bricks had fallen off another high-rise, leaving cracks and holes in the walls.

The quake also set off at least nine landslides on Suhua Highway in Hualien, according to Taiwan’s Central News Agency, which said part of the road had collapsed.

Taiwan’s fire department said four people had been killed in the earthquake.

Across Taiwan, 40 flights have been canceled or delayed because of the earthquake, according to Taiwan’s Central Emergency Operation Center.

President Tsai Ing-wen visited Taiwan’s national emergency response center this morning, where she was briefed about the response efforts underway by members of the ministries of defense, transportation, economic affairs and agriculture, as well as the fire department.

A look at Taiwan’s strongest earthquakes.

The magnitude 7.4 earthquake that hit Taiwan on Wednesday morning was the strongest in 25 years, the island’s Central Weather Administration said.

At least four people died after the quake struck off Taiwan’s east coast, officials said.

Here’s a look back at some of the major earthquakes in modern Taiwanese history:

Taichung, 1935

Taiwan’s deadliest quake registered a magnitude of 7.1 and struck near the island’s west coast in April 1935, killing more than 3,200 people, according to the Central Weather Administration. More than 12,000 others were injured and more than 50,000 homes were destroyed or damaged.

Tainan, 1941

A magnitude 7.3 earthquake in December 1941, which struck southwestern Taiwan, caused several hundred deaths, the United States Geological Survey said.

Chi-Chi, 1999

A 7.6 magnitude earthquake in central Taiwan killed nearly 2,500 people in September 1999. The quake, which struck about 90 miles south-southwest of Taipei, was the second-deadliest in the island’s history, according to the U.S.G.S. and the Central Weather Administration. More than 10,000 people were injured and more than 100,000 homes were destroyed or damaged.

Yujing, 2016

A 6.4 magnitude earthquake in February 2016 caused a 17-story apartment complex in southwestern Taiwan to collapse, killing at least 114 people . The U.S.G.S. later said that 90 earthquakes of that scale or greater had occurred within 250 kilometers, or 155 miles, of that quake’s location over the previous 100 years.

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COMMENTS

Implantation Failure: What Can Prevent It From Happening?
While there are many myths out there surrounding getting pregnant, when it comes to implantation, there are few things a woman can do to prevent it from happening. Strenuous exercises are unlikely to prevent implantation. Straining with bowel movements, for example, will not impact embryo implantation. Constipation is a common side effect of ...
How to Help Implantation: Can You Boost Your Chances for Pregnancy?
They are not good for implantation, as they can affect the ability of the uterus to extend protrusions of the uterine lining to dock with the embryo. One study found an 80% increased risk of early miscarriage with anti-inflammatory use around the time of conception. Anti-inflammatory medication is also not good for young embryos post-implantation.
Should I avoid travelling during implantation?
Does stress from travelling during implantation affect the chances of successful implantation? High levels of stress can potentially have a negative impact on the implantation process. Traveling, especially long-distance travel, can be stressful for some individuals. It is essential to prioritize relaxation and stress-reducing strategies during ...
Is Travelling safe during implantation?
Travelling during implantation is a commonly asked question among women who are trying to conceive or have recently found out that they are pregnant. Implantation refers to the process where a fertilized egg attaches itself to the wall of the uterus, and it typically occurs around 6-12 days after ovulation.
Do's and Don'ts after your Embryo Transfer
Raising your body temperature can potentially affect the implantation of the embryo and lead to a lower success rate. So, don't do this after your embryo transfer. ... Avoid inhaling petrol and diesel fumes by travelling through areas with less traffic or travelling at a time when the traffic is minimal. If you have any concerns, ...
Implantation during pregnancy: Symptoms, timeline, and testing
Implantation is a critical early stage in every pregnancy. Implantation symptoms can include light bleeding, cramping, nausea, bloating, sore breasts, headaches, and mood swings. This article ...
Embryo Implantation: What Affects Implantation?
Implantation is the next step after fertilization in the reproductive process. Once an ovulated egg meets sperm in the fallopian tube and gets fertilized, the fertilized egg (now called an embryo) travels down the fallopian tube, enters the uterus and attaches itself to the wall of the uterus. Typically, implantation happens somewhere between 6 ...
Implantation: What Is It? And When Does It Happen?
Your cycle. Health 360°. Getting pregnant. Pregnancy. Implantation is an important part of conception, but what does implantation mean, when does it happen and what are the signs? Find out everything you need to know about implantation here.
Implantation and the Start of Pregnancy
Ovulation: In order to become pregnant, you need to ovulate (release an egg from an ovary into the fallopian tube). Ejaculation: After sex, sperm travel through the vagina, past the cervix and up into the fallopian tubes. This is where the sperm will most likely join with an available egg. Fertilization: When the sperm joins the egg and ...
When Does Implantation Occur? Symptoms, What to Expect
When does implantation occur? Implantation occurs about eight to nine days after fertilization, though it can happen as early as six days and as late as 12 days after ovulation. Put another way: "If a woman has a regular 28-day menstrual cycle, ovulation typically occurs around day 14 of the cycle, and implantation may occur between days 20 ...
9 Things To Remove To Increase Implantation Success
Everyday Things To Remove To Increase Implantation Success. 1. Taking Anti-Inflammatories. Anti-inflammatories are a class of medications that reduce swelling and inflammation in the body. Some common over-the-counter medications (also known as NSAIDs) are Advil, Aleve and Motrin.
What Affects Implantation and How to Make It Successful
Fertilization occurs when the female egg meets the male sperm in the fallopian tube. After fertilization, the next big step is implantation. Once the fertilized egg travels through the fallopian tube it will find a place to settle in the womb. Think of implantation as the union between your egg and your womb. This fertilized egg, also known as ...
5 Essential Things To Avoid During Implantation
Embryo implantation happens when an embryo binds to the wall of the womb in the endometrial lining. At this time, you need to avoid 5 things during implantation include use of anti-inflammatories, intake of excessiv caffeine, hot tubs, saunas, hot yoga, exercise, sexual Intercourse, high glycemic foods.
Can I fly after my fertility treatment? IVF Travel Tips
In short, patients can fly after insemination or IVF. Implantation ultimately depends upon a healthy embryo finding the right spot in a healthy uterine lining. The success of the subsequent pregnancy depends upon factors that far outweigh any added radiation exposure from a flight. If you would like to learn more about GENESIS Fertility New ...
Will travelling affect implantation?
Travelling is a common aspect of our lives, whether it be for work or pleasure. However, for couples trying to conceive, concerns about how travel can impact implantation may arise. So, does travelling affect implantation? The short answer is no, it doesn't. Travelling itself does not directly impact the process of implantation.
Can you travel to high altitudes while pregnant?
Take care while traveling to high altitudes while pregnant: It isn't always recommended, depending on where you go and how you respond to being there. At high altitudes, less oxygen is available, which means you'll tire more easily. It also means your baby will get less oxygen, which can negatively affect growth and development.
Safe Flying During IVF & First 12 Weeks
IVF Turkey's clients travel from all over the world for their impeccable program of care. They also know a thing or two about those all-important first 12 weeks, and flying when pregnant, after IVF. ... And in most cases, our answer is flying doesn't affect implantation as a standalone factor. Successful implantation is mainly about two ...
Does Travelling After Embryo Transfer Affects The Pregnancy Outcome
Therefore, travelling per se will not affect any of the above factors responsible for implantation of embryo. Earlier there were many studies to evaluate the effect of bed rest on pregnancy rates after embryo transfer. This is the first study to compare the pregnancy rates in patients who travelled to their countries with the patients who ...
What Happens After Implantation? The Process of Conception Explained
Implantation pain: When the egg implants into the lining of the uterus, you may experience mild abdominal cramping, similar to menstrual cramps. This is commonly referred to as implantation cramps. If implantation takes place, you may experience some of the following early pregnancy symptoms: Tender breasts. Nausea.
What to do after embryo transfer?
When to test for pregnancy. In natural pregnancies, the embryo attaches to the uterine lining about 6 to 8 days after entering the uterus. This means that embryo implantation occurs at blastocyst stage. In short, even though this is the precise moment when implantation takes place, the entire process can take up to one week to be fully completed.
Is it safe to travel by a two or three wheeler during pregnancy?
In general, doctors recommend that for the duration of your pregnancy, you don't travel by a two-wheeler. If you're a passionate motorbike rider and feel very confident about continuing, speak to your doctor to be sure it's safe for you. You might be able to continue in your first trimester, but will be asked to stop when your baby bump starts ...
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The stunning collapse of the Francis Scott Key Bridge on Tuesday will have economic impacts far beyond the city of Baltimore. The big picture: The Port of Baltimore, one of the busiest in the U.S., has halted vessel traffic indefinitely in the wake of the bridge's collapse — which is expected to affect the flow of commerce in the U.S.
Can I travel during implantation days?
ContentsCan I travel during implantation days?FAQs about traveling during implantation days:1. Can travel affect the chances of successful implantation?2. Are there any specific precautions I should take while traveling during the implantation phase?3. Can flying affect implantation?4. Are there any travel restrictions during the implantation phase?5.
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